PU¶PubMed·Journal article·Tinnitus·4w agoApplication of neurodegenerative disease treatment strategies in tinnitus: mechanisms, translation, and prospectsFraming tinnitus within the neurodegenerative plasticity paradigm could open new drug and neuromodulation treatment pipelines, potentially accelerating therapeutic development for a condition with no FDA-approved pharmacotherapy.＋Save
PU¶PubMed·Journal article·Vestibular·4w agoAssessment of balance control mechanisms in patient populations using perturbation-based modeling: a narrative review with clinical implicationsAdvancing computational models of balance assessment could improve vestibular diagnostics, helping audiologists and vestibular specialists identify and quantify sensorimotor deficits more precisely in patients with dizziness or falls risk.＋Save
PU¶PubMed·Journal article·Research (general)·4w agoTesting differential effects of periodicity and predictability in auditory rhythmic cueing of concurrent speechUnderstanding how the brain uses rhythmic timing to separate speech from noise could eventually inform new signal-processing strategies in hearing aids and cochlear implants.＋Save
PU¶PubMed·Journal article·Research (general)·4w agoDural arteriovenous fistula of the hypoglossal canal treated with endovascular embolization using 3D Slicer-based preoperative planning: Case reportThis case highlights the value of advanced preoperative imaging software (3D Slicer) in planning endovascular treatment of rare causes of pulsatile tinnitus, reinforcing the need for audiologists to refer pulsatile tinnitus cases for vascular imaging.＋Save
Hearing Practitioner Australia·Journal article·Hearing aids·4w agoEffective hearing aid use linked to lower dementia risk in international studyThis study adds meaningful observational evidence supporting consistent hearing aid use in older adults as a potential modifiable factor for dementia risk reduction — audiologists should reinforce adherence counselling, though causation is not yet established.＋Save
PU¶PubMed·Journal article·Tinnitus·4w agoCurrent status and future prospects of research on psilocybin's regulation of neurotransmitters and their receptors related to the pathogenesis of tinnitusAs tinnitus lacks effective pharmacological treatments, mapping psilocybin's neurotransmitter interactions with tinnitus pathways could open novel therapeutic avenues, making this a scientifically timely area of inquiry.＋Save
PU¶PubMed·Journal article·Cochlear implants·4w agoEffects of Talker Sex Differences on Binaural Summation in Cochlear Implant Users and Normal Hearing ListenersFindings on talker sex differences in binaural summation for CI users may inform bilateral implant counselling and programming strategies, but replication in larger samples is needed before changing clinical protocols.＋Save
PU¶PubMed·Journal article·Research (general)·4w agoLong-term Outcomes of Hypo- and Conventional Fractionated Stereotactic Radiotherapy for Non-vestibular Schwannomas: A Retrospective Cohort Study from Ramathibodi HospitalSchwannomas can affect hearing and cranial nerve function; clarifying optimal radiotherapy fractionation helps guide neuro-oncology teams and informs audiological monitoring protocols for affected patients.＋Save
PU¶PubMed·Journal article·Vestibular·4w agoAssessing the relationships between migraine and driving risks, challenges and coping strategiesMigraine's multisensory integration demands during driving represent a poorly recognised disability burden, and audiologists treating vestibular migraine or hyperacusis (sound sensitivity) patients may need to include driving-related counselling in care plans.＋Save
PU¶PubMed·Journal article·Cochlear implants·4w agoDevelopment of an Orff music-based intervention program based on the PERMA model for children with cochlear implants: a Delphi studyIntegrating structured music-based rehabilitation with well-being frameworks like PERMA may offer a novel adjunct to conventional auditory training for pediatric cochlear implant users, but empirical outcome data are still needed.＋Save
PU¶PubMed·Journal article·Research (general)·5w agoNeuro-visual pathway after mild traumatic brain injury: a systematic scoping review of symptoms, objective testing, and rehabilitationAudiologists managing patients with mild traumatic brain injury (mTBI) should be aware of co-occurring neuro-visual symptoms, though this scoping review does not yet support specific protocol changes — multidisciplinary referral pathways remain the appropriate response.＋Save
PU¶PubMed·Journal article·Cochlear implants·5w agoElectroactive nanostructured polypyrrole coatings with on-demand drug release for immunomodulation of neural electrode interfacesReducing immune-driven inflammation at neural electrode interfaces is a fundamental challenge for cochlear implants and other auditory neuroprosthetics; advances in electrode coatings could eventually improve long-term implant performance.＋Save
PU¶PubMed·Journal article·Vestibular·5w agoIncreased head-turning, hyperactivity and low-penetrance circling behaviour in mice lacking ZPLD1, a protein that scaffolds the cupula to the roof of the ampullaIdentifying ZPLD1 as a structural scaffolding protein for the cupula advances the molecular understanding of vestibular function and opens a potential pathway for investigating genetic causes of balance disorders in humans.＋Save
PU¶PubMed·Journal article·Research (general)·5w agoAQP4-Mediated Glymphatic Clearance: Sleep, Neurodegeneration, and the Translational GapThe glymphatic system's role in clearing neurodegenerative waste during sleep may eventually help explain links between sleep disruption, hearing loss, and dementia risk that audiologists encounter clinically.＋Save
PU¶PubMed·Journal article·Research (general)·5w agoVisually challenging conditions on sign language intelligibility show behavioural analogies with spoken languageDemonstrating cross-modal parallels between visual sign language and auditory spoken language perception deepens our understanding of how the brain processes language under degraded sensory conditions, with implications for rehabilitation and communication accessibility research.＋Save
Hearing Practitioner Australia·Industry news·Research (general)·5w agoSensorion pivots to new gene therapy for hearing loss: Australian trial plans underwayGJB2 mutations are the single most common cause of inherited deafness, so a targeted gene therapy entering clinical trials could eventually offer a biological treatment option alongside conventional amplification for a well-defined patient population.＋Save
Hearing Health Matters·Press release·Research (general)·5w agoAcousia Reports Promising First-in-Patient Phase 2a Results for ACOU085 in Cisplatin-Induced OtotoxicityIf confirmed in larger trials, a drug that prevents chemotherapy-related hearing damage (ototoxicity) could significantly reduce one of the most common and life-altering side effects of cisplatin-based cancer treatment.＋Save
Hearing Review·Press release·Research (general)·5w agoSensorion Names SENS-601 Lead Gene Therapy Program, Files Clinical Trial Applications for GJB2-Related Hearing LossGJB2 mutations are the most frequent genetic cause of congenital deafness, so a successful AAV gene therapy could eventually offer a biological treatment option for a large portion of patients with hereditary hearing loss.＋Save
RNID·Other·Research (general)·5w agoTargeting mitochondria to protect against noise-induced hearing lossIdentifying the mitochondrial pathways driving noise-induced hearing damage could open entirely new pharmacological prevention strategies for an extremely common and currently irreversible condition.＋Save
RNID·Other·Research (general)·5w agoDeveloping gene therapy for TOMT-linked hearing lossTOMT-linked hearing loss is a distinct genetic subtype, and targeted gene therapies for specific mutations represent the frontier of curative audiology research.＋Save
RNID·Other·Research (general)·5w agoInvestigating the feasibility of gene therapy for stereocilin-related hearing lossStereocilin mutations cause a specific inherited form of hearing loss, and a successful gene therapy could one day offer a curative option beyond hearing aids or cochlear implants.＋Save
RNID·Other·Hearing aids·5w agoEvaluating a novel signal-processing strategy for improving perception of speechA successful new signal-processing strategy for noisy environments would directly address one of the most common and persistent complaints of hearing-aid users, potentially improving device satisfaction and uptake.＋Save
RNID·Other·Tinnitus·5w agoDisentangling brain activity underlying hyperacusis and tinnitusIdentifying distinct brain-level mechanisms for hyperacusis versus tinnitus could pave the way for condition-specific diagnostic tools and therapies, which are currently lacking.＋Save
RNID·Other·Research (general)·5w agoReal-time monitoring of listening effort and fatigue in older adultsValidated real-world measures of listening effort and fatigue could fill a major gap in audiological assessment, enabling more person-centred rehabilitation for older adults.＋Save
PU¶PubMed·Journal article·Research (general)·5w agoInterplay of age, speech perception in noise, standard and extended high-frequency hearing, and cochlear synaptopathy in individuals with normal audiogramsExtended high-frequency audiometry and cochlear synaptopathy measures may help explain speech-in-noise difficulties in patients with normal standard audiograms, but routine clinical adoption requires further validation before practice change is warranted.＋Save
PU¶PubMed·Journal article·Tinnitus·5w agoEvaluation of Cochlear Function, Hidden Hearing Loss, and Auditory Temporal Processing in Tinnitus Patients with Normal AudiogramsHidden hearing loss and auditory temporal processing measures may reveal underlying dysfunction in tinnitus patients with normal audiograms, but findings need replication in larger controlled trials before changing clinical evaluation protocols.＋Save
PU¶PubMed·Journal article·Vestibular·5w agoIntraoperative High Resolution 2D and 3D Angiography in Cervical Decompression for Sub-Axial Bow Hunter's SyndromeBow Hunter's Syndrome can mimic inner ear disorders, so audiologists and neurotologists should be aware of this rare vascular diagnosis when patients report position-dependent dizziness or sudden auditory symptoms.＋Save
PU¶PubMed·Journal article·Vestibular·5w agoNeurological complications in microgravity and long duration spaceflightSpaceflight-induced neuro-otological changes — including vestibular and possibly auditory pathway alterations — may offer extreme-environment insights relevant to understanding balance and hearing disorders more broadly.＋Save
PU¶PubMed·Journal article·Vestibular·5w agoTumor-to-Tumor Metastasis Involving Vestibular Schwannoma: Case Report and Literature ReviewTumor-to-tumor metastasis involving vestibular schwannoma is exceedingly rare, and awareness of this entity may prevent misdiagnosis and guide appropriate pathologic evaluation in atypical cases.＋Save
