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Interplay of age, speech perception in noise, standard and extended high-frequency hearing, and cochlear synaptopathy in individuals with normal audiograms

A dispatch from PubMed — filed

Older adults often complain about having difficulty understanding speech in noise, despite clinically normal hearing (D-SiN-NH). Two otopathologies known to decline with age and that are not reflected in the conventional audiogram are extended high-frequency (EHF) hearing impairment and cochlear synaptopathy (CS), both hypothesized to be responsible for D-SiN-NH....

Clinical Takeaway

Extended high-frequency audiometry and cochlear synaptopathy measures may help explain speech-in-noise difficulties in patients with normal standard audiograms, but routine clinical adoption requires further validation before practice change is warranted.

Why It Matters

This study advances understanding of why patients with clinically normal audiograms still report hearing difficulties, potentially reshaping how audiologists evaluate and counsel this population.

Key Points
  1. 01Targets adults with normal conventional audiograms who nonetheless experience hearing difficulties.
  2. 02Examines the role of cochlear synaptopathy (hidden nerve damage) alongside age-related factors.
  3. 03Includes extended high-frequency (EHF) hearing measures beyond the standard audiogram range.
  4. 04Speech-in-noise perception is a core outcome, reflecting real-world hearing challenges.
  5. 05Published in Hearing Research, a peer-reviewed audiology journal.
Claims & Evidence

Age, speech-in-noise perception, extended high-frequency hearing, and cochlear synaptopathy are interrelated in adults with normal audiograms.

studypartially supported

Cochlear synaptopathy contributes to hearing difficulties in individuals who pass standard audiometric screening.

studypartially supported
Research metadata
PMID
42284997
DOI
10.1016/j.heares.2026.109706.
Journal
Hearing Research
Publication type
research_article
Evidence level
2b
Population
Adults with clinically normal audiograms
Intervention
Assessment of age, extended high-frequency hearing, and cochlear synaptopathy measures

Primary outcomes

Speech-in-noise perception; Extended high-frequency hearing thresholds; Cochlear synaptopathy markers

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