PU¶PubMed·Journal article·Vestibular·5d agoDeficits in tail-lift and air-righting reflexes in rats after ototoxicity associate with loss of vestibular type I hair cellsIdentifying the specific vestibular hair cell type responsible for functional balance deficits after ototoxicity could eventually guide the development of targeted protective or regenerative therapies.
PU¶PubMed·Journal article·Vestibular·12d agoDetailed vestibular subtyping and prognostic implications in idiopathic sudden sensorineural hearing lossDetailed vestibular subtyping at diagnosis of ISSNHL may offer prognostic value for predicting hearing recovery, supporting the case for comprehensive vestibular testing as part of the ISSNHL workup — though clinical adoption should await prospective validation.＋Save
PU¶PubMed·Journal article·Tinnitus·2w agoCurrent status and future prospects of research on psilocybin's regulation of neurotransmitters and their receptors related to the pathogenesis of tinnitusAs tinnitus lacks effective pharmacological treatments, mapping psilocybin's neurotransmitter interactions with tinnitus pathways could open novel therapeutic avenues, making this a scientifically timely area of inquiry.＋Save
PU¶PubMed·Journal article·Vestibular·2w agoIncreased head-turning, hyperactivity and low-penetrance circling behaviour in mice lacking ZPLD1, a protein that scaffolds the cupula to the roof of the ampullaIdentifying ZPLD1 as a structural scaffolding protein for the cupula advances the molecular understanding of vestibular function and opens a potential pathway for investigating genetic causes of balance disorders in humans.＋Save
PU¶PubMed·Journal article·Research (general)·2w agoInterplay of age, speech perception in noise, standard and extended high-frequency hearing, and cochlear synaptopathy in individuals with normal audiogramsExtended high-frequency audiometry and cochlear synaptopathy measures may help explain speech-in-noise difficulties in patients with normal standard audiograms, but routine clinical adoption requires further validation before practice change is warranted.＋Save
PU¶PubMed·Journal article·Cochlear implants·3w agoElectrically evoked compound action potentials in adult and pediatric cochlear implant users: II. Assessing cochlear nerve health status with the interphase gap effect and the phase locking valueThe interphase gap effect and phase locking value may offer clinically useful, objective measures of cochlear nerve health in CI users, but findings require validation in larger prospective studies before changing routine programming or counseling practice.＋Save
PU¶PubMed·Journal article·Research (general)·4w agoAging-related reconfiguration of auditory working-memory control under converging phonological and executive demands: EEG signatures and speech-in-noise performanceIdentifying the neural signatures of age-related auditory working-memory decline in normal-audiogram older adults may explain why some patients struggle with speech-in-noise despite passing standard audiograms.＋Save
PU¶PubMed·Journal article·Research (general)·4w agoStress across timescales: differential effects of acute and chronic stress on auditory processing and perceptionClarifying the mechanistically distinct effects of acute versus chronic stress on auditory processing could reshape how audiologists interpret unexplained auditory complaints and guide future research into stress-related hearing difficulties.＋Save
PU¶PubMed·Journal article·Cochlear implants·4w agoFeasibility analysis of an implantable middle ear cavity pressure microphoneThis is a feasibility study at an early engineering stage; no clinical practice change is warranted, but audiologists should follow this line of research as it could reshape fully implantable cochlear implant counseling in the future.＋Save
PU¶PubMed·Journal article·Tinnitus·5w agoFunctional near-infrared spectroscopy (fNIRS) biomarkers of tinnitus severity within tinnitus subtypesAn objective, brain-based measure of tinnitus severity would fill a critical gap in diagnosis and treatment monitoring, since clinicians currently rely entirely on patient self-report.＋Save
PU¶PubMed·Journal article·Research (general)·5w agoMineralocorticoid and glucocorticoid receptors in the mammalian inner ear: a scoping reviewThis scoping review provides foundational receptor-distribution data that may help refine corticosteroid treatment strategies for sudden sensorineural hearing loss and Ménière's disease, but no immediate protocol changes are warranted pending further clinical trials.＋Save
PU¶PubMed·Journal article·Cochlear implants·5w agoTemporal evolution of impedance after motorized versus manual cochlear implantationCochlear implant surgeons should monitor how insertion method (motorized vs. manual) affects post-operative impedance trajectories, particularly in hearing-preservation candidates, though definitive practice change awaits larger controlled trials.＋Save
PU¶PubMed·Journal article·Clinical audiology·5w agoSpeech-in-noise difficulties in aminoglycoside ototoxicity reflects combined afferent and efferent dysfunctionAudiologists monitoring patients on chronic aminoglycoside therapy should assess both afferent (hearing nerve) and efferent (brain-to-ear tuning) function, as speech-in-noise difficulties in this population reflect dual-pathway dysfunction beyond standard audiometric thresholds.＋Save
PU¶PubMed·Journal article·Tinnitus·6w agoHyperacusis-inducing drug candidatesAudiologists should be aware that certain drug classes may trigger or worsen hyperacusis; this review may prompt more careful medication history-taking in hyperacusis patients, but specific clinical protocols await further research.＋Save
PU¶PubMed·Journal article·Cochlear implants·2mo agoDesign and evaluation of back-end compressors for compressed content for cochlear implant usersNo immediate practice change; findings are relevant to device signal processing engineers and could eventually inform streaming settings in future cochlear implant sound processors, but no clinician-adjustable protocol exists yet.＋Save
