PU¶PubMed·Journal article·Tinnitus·19h agoBiomarkers of Subjective Tinnitus Presence and Clinical Burden: A Systematic ReviewIdentifying reliable objective biomarkers for tinnitus could transform diagnosis, patient stratification, and treatment-outcome measurement, addressing a longstanding gap in tinnitus clinical research.
PU¶PubMed·Journal article·Clinical audiology·1d agoHyperacusis scores and listening characteristics: Extended high-frequency audiograms from a young population without tinnitus and with low noise exposureUnderstanding how extended high-frequency hearing relates to hyperacusis sensitivity in young, noise-naïve adults may help establish baseline norms and early markers before overt auditory damage develops.＋Save
PU¶PubMed·Journal article·Tinnitus·4d agoAsymmetry of vestibular pathways predicts upper-brainstem auditory imbalance in subjective somatosensory tinnitus: A tract-specific chronological reorganization modelThis mechanistic model linking vestibular pathway asymmetry to somatic tinnitus is preliminary and hypothesis-generating; no change to clinical assessment or treatment protocols is warranted based on this single study.＋Save
PU¶PubMed·Journal article·Cochlear implants·6d agoElectrically evoked compound action potentials in adult and pediatric cochlear implant users: I. Cochlear nerve responsiveness and electrode-neuron interface indexFindings are preliminary; await full results and replication before adjusting cochlear implant fitting or programming protocols based on age-group differences in nerve responsiveness.＋Save
PU¶PubMed·Journal article·Research (general)·7d agoCortical speech-in-noise processing reflects subcortical syllable encoding and lexical attentionNo actionable practice change yet; findings advance understanding of why speech-in-noise ability varies among people with similar audiograms, but do not yet translate to a clinical protocol or test.＋Save
PU¶PubMed·Journal article·Cochlear implants·11d agoRelationships between ECAP amplitude growth functions and perceptual growth in cochlear implant users: Implications for individualized cochlear implant fittingIf ECAP amplitude growth functions show a meaningful correlation with perceptual loudness growth, audiologists may be able to use objective measures to streamline or partially automate cochlear implant fitting, reducing reliance on subjective patient feedback — worth monitoring...＋Save
PU¶PubMed·Journal article·Vestibular·3w agoNear-field recordings expose the limits of far-field measures of peripheral vestibular nerve activity: implications for experimental controlsDemonstrating that far-field VsEP recordings have meaningful limitations challenges a widely used methodological assumption in vestibular research, potentially prompting reassessment of published experimental controls across many prior studies.＋Save
PU¶PubMed·Journal article·Cochlear implants·3w agoImplicit auditory sensory memory and short-term memory for musical and verbal stimuli in children with cochlear implantsThis study provides mechanistic insight into auditory memory limitations in pediatric CI users but does not yet offer direct clinical protocols; audiologists should be aware that spectrally degraded signals may impair sequential auditory encoding, which could inform future aural...＋Save
PU¶PubMed·Journal article·Research (general)·4w agoAn optimized tissue processing pipeline for multiscale imaging of the intact peripheral auditory pathwayA reliable, optimized pipeline for intact multiscale imaging of the peripheral auditory pathway could accelerate basic research into cochlear structure, hearing loss mechanisms, and implant biology.＋Save
PU¶PubMed·Journal article·Cochlear implants·4w agoComparative spatiotemporal dynamics of access resistance, polarization impedance, and nested bipolar impedance in standard and dexamethasone-eluting electrode arraysDexamethasone-eluting electrode arrays may reduce intracochlear fibrosis and immune response as reflected by impedance dynamics, but clinicians should await peer-reviewed outcome data on hearing preservation and speech perception before preferring these arrays over standard ones.＋Save
PU¶PubMed·Journal article·Cochlear implants·6w agoElectrophysiologically-based electrode selection has the potential to improve speech perception in cochlear-implant usersElectrophysiology-based electrode selection is a promising approach to improving cochlear implant (CI) programming, but current evidence is preliminary; audiologists should monitor emerging protocols before adopting routine clinical changes.＋Save
PU¶PubMed·Journal article·Research (general)·6w agoSpeech-in-noise recognition during hearing protector use: Human performance and acoustic predictionNo actionable practice change now; findings may eventually improve hearing protector selection guidance for workers who must communicate in noise, but clinical translation awaits further validation.＋Save
PU¶PubMed·Journal article·Vestibular·6w agoTGF-β signaling regulates flat epithelium formation in severely injured adult mouse utricle through epithelial-mesenchymal transitionUnderstanding how scar tissue forms in the injured inner ear balance organ is a key barrier to developing regenerative treatments for vestibular disorders.＋Save
PU¶PubMed·Journal article·Vestibular·7w agoDeficits in tail-lift and air-righting reflexes in rats after ototoxicity associate with loss of vestibular type I hair cellsIdentifying the specific vestibular hair cell type responsible for functional balance deficits after ototoxicity could eventually guide the development of targeted protective or regenerative therapies.＋Save
PU¶PubMed·Journal article·Vestibular·8w agoDetailed vestibular subtyping and prognostic implications in idiopathic sudden sensorineural hearing lossDetailed vestibular subtyping at diagnosis of ISSNHL may offer prognostic value for predicting hearing recovery, supporting the case for comprehensive vestibular testing as part of the ISSNHL workup — though clinical adoption should await prospective validation.＋Save
PU¶PubMed·Journal article·Tinnitus·2mo agoCurrent status and future prospects of research on psilocybin's regulation of neurotransmitters and their receptors related to the pathogenesis of tinnitusAs tinnitus lacks effective pharmacological treatments, mapping psilocybin's neurotransmitter interactions with tinnitus pathways could open novel therapeutic avenues, making this a scientifically timely area of inquiry.＋Save
PU¶PubMed·Journal article·Vestibular·2mo agoIncreased head-turning, hyperactivity and low-penetrance circling behaviour in mice lacking ZPLD1, a protein that scaffolds the cupula to the roof of the ampullaIdentifying ZPLD1 as a structural scaffolding protein for the cupula advances the molecular understanding of vestibular function and opens a potential pathway for investigating genetic causes of balance disorders in humans.＋Save
PU¶PubMed·Journal article·Research (general)·2mo agoInterplay of age, speech perception in noise, standard and extended high-frequency hearing, and cochlear synaptopathy in individuals with normal audiogramsExtended high-frequency audiometry and cochlear synaptopathy measures may help explain speech-in-noise difficulties in patients with normal standard audiograms, but routine clinical adoption requires further validation before practice change is warranted.＋Save
PU¶PubMed·Journal article·Cochlear implants·2mo agoElectrically evoked compound action potentials in adult and pediatric cochlear implant users: II. Assessing cochlear nerve health status with the interphase gap effect and the phase locking valueThe interphase gap effect and phase locking value may offer clinically useful, objective measures of cochlear nerve health in CI users, but findings require validation in larger prospective studies before changing routine programming or counseling practice.＋Save
PU¶PubMed·Journal article·Research (general)·2mo agoAging-related reconfiguration of auditory working-memory control under converging phonological and executive demands: EEG signatures and speech-in-noise performanceIdentifying the neural signatures of age-related auditory working-memory decline in normal-audiogram older adults may explain why some patients struggle with speech-in-noise despite passing standard audiograms.＋Save
PU¶PubMed·Journal article·Research (general)·2mo agoStress across timescales: differential effects of acute and chronic stress on auditory processing and perceptionClarifying the mechanistically distinct effects of acute versus chronic stress on auditory processing could reshape how audiologists interpret unexplained auditory complaints and guide future research into stress-related hearing difficulties.＋Save
PU¶PubMed·Journal article·Cochlear implants·2mo agoFeasibility analysis of an implantable middle ear cavity pressure microphoneThis is a feasibility study at an early engineering stage; no clinical practice change is warranted, but audiologists should follow this line of research as it could reshape fully implantable cochlear implant counseling in the future.＋Save
PU¶PubMed·Journal article·Tinnitus·2mo agoFunctional near-infrared spectroscopy (fNIRS) biomarkers of tinnitus severity within tinnitus subtypesAn objective, brain-based measure of tinnitus severity would fill a critical gap in diagnosis and treatment monitoring, since clinicians currently rely entirely on patient self-report.＋Save
PU¶PubMed·Journal article·Research (general)·2mo agoMineralocorticoid and glucocorticoid receptors in the mammalian inner ear: a scoping reviewThis scoping review provides foundational receptor-distribution data that may help refine corticosteroid treatment strategies for sudden sensorineural hearing loss and Ménière's disease, but no immediate protocol changes are warranted pending further clinical trials.＋Save
PU¶PubMed·Journal article·Cochlear implants·2mo agoTemporal evolution of impedance after motorized versus manual cochlear implantationCochlear implant surgeons should monitor how insertion method (motorized vs. manual) affects post-operative impedance trajectories, particularly in hearing-preservation candidates, though definitive practice change awaits larger controlled trials.＋Save
PU¶PubMed·Journal article·Clinical audiology·2mo agoSpeech-in-noise difficulties in aminoglycoside ototoxicity reflects combined afferent and efferent dysfunctionAudiologists monitoring patients on chronic aminoglycoside therapy should assess both afferent (hearing nerve) and efferent (brain-to-ear tuning) function, as speech-in-noise difficulties in this population reflect dual-pathway dysfunction beyond standard audiometric thresholds.＋Save
PU¶PubMed·Journal article·Tinnitus·3mo agoHyperacusis-inducing drug candidatesAudiologists should be aware that certain drug classes may trigger or worsen hyperacusis; this review may prompt more careful medication history-taking in hyperacusis patients, but specific clinical protocols await further research.＋Save
PU¶PubMed·Journal article·Cochlear implants·3mo agoDesign and evaluation of back-end compressors for compressed content for cochlear implant usersNo immediate practice change; findings are relevant to device signal processing engineers and could eventually inform streaming settings in future cochlear implant sound processors, but no clinician-adjustable protocol exists yet.＋Save
