PU¶PubMed·Journal article·Research (general)·7w agoGadd45a knockout alleviates cisplatin-induced hearing loss by inhibiting CXCL family protein expressionThis is a mouse study identifying a potential molecular target for preventing cisplatin-related hearing damage; no actionable change in clinical practice is warranted at this stage.+Save
The Audiology Project·Blog·Vestibular·8w agoPrep for Fall Prevention Month: Skilled Nursing and Long-term Care FacilitiesAudiologists working in skilled nursing and long-term care settings should use Fall Prevention Month in September as a structured opportunity to review their balance assessment protocols and fall-risk screening workflows for residents — this is a practice-reinforcement reminder...+Save
PU¶PubMed·Journal article·Vestibular·8w agoMultidisciplinary practice in vestibular schwannoma surgery over a decade: optimizing facial nerve and hearing outcomes and analyzing the predictive role of tumor-related radiological featuresTumor-specific radiological features may help predict facial nerve and hearing preservation outcomes before vestibular schwannoma surgery, which could inform surgical planning and patient counseling — but the specific predictive variables and effect sizes should be reviewed...+Save
PU¶PubMed·Journal article·Vestibular·8w agoThe Vestibular System Influences the Perceived Duration of Lights But Not of Sounds or TouchesUnderstanding that vestibular input selectively distorts visual — but not auditory or tactile — duration perception deepens our model of multisensory timing and may inform future research on vestibular-related perceptual disorders.+Save
PU¶PubMed·Journal article·Vestibular·8w agoShort-term factual recall, presence, and visio-vestibular discomfort in a 360 augmented-virtuality classroom environment: A feasibility studyAs immersive extended-reality environments are explored for audiology education and aural rehabilitation, early feasibility data on cognitive load, presence, and VR-related discomfort help frame what future clinical or training applications must address.+Save
PU¶PubMed·Journal article·Vestibular·8w agoThe Price of Paralysis: Analyzing the Direct Cost of Facial Rehabilitation after Vestibular Schwannoma ResectionFacial paralysis is a significant quality-of-life complication of vestibular schwannoma resection, and quantifying rehabilitation costs supports shared decision-making, insurance advocacy, and surgical outcome benchmarking.+Save
PU¶PubMed·Journal article·Vestibular·8w agoGenetic contributions to familial Ménière's disease: a systematic reviewIdentifying hereditary genetic variants linked to Ménière's disease could eventually enable earlier diagnosis and targeted treatment for the subset of patients with a familial form of the condition.+Save
PU¶PubMed·Journal article·Vestibular·8w agoManagement strategies for vestibular schwannomas in patients with NF2-related schwannomatosis: a systematic reviewA synthesis of management strategies for this rare but devastating condition helps neurotology and audiology teams weigh surgery, radiation, observation, and emerging medical therapies for a patient population with very limited options.+Save
PU¶PubMed·Journal article·Vestibular·8w agoTargeted Vestibular Rehabilitation Accelerates Symptom Relief by Promoting Vestibular Compensation in BPPV Patients With Residual Symptoms: Evidence From Resting-State fMRITargeted vestibular rehabilitation therapy should be considered for BPPV patients with residual dizziness after canalith repositioning, as fMRI evidence now provides a neurological basis for its benefit in this subgroup.+Save
PU¶PubMed·Journal article·Vestibular·8w agoVestibular schwannoma associated normal pressure hydrocephalus: clinical features and shunt responsiveness compared with idiopathic NPHAudiologists should be aware that vestibular schwannoma patients can develop NPH, as this may influence referral pathways, but direct clinical practice change for audiology is limited — this is primarily a neurosurgical concern.+Save
PU¶PubMed·Journal article·Vestibular·8w agoHybrid Microvascular Decompression For Cranial Neurovascular Compression Syndromes: A Retrospective Case Series and Surgical NuancesAdvances in microvascular decompression technique could reduce surgical complications for patients with cranial neurovascular compression syndromes, some of whom present initially to audiologists with tinnitus or hyperacusis.+Save
PU¶PubMed·Journal article·Vestibular·8w agoCorrection: Transcriptome-wide profiling of cystic and solid vestibular schwannomas reveals candidate long non-coding RNA signaturesCorrection notices maintain the integrity of the scientific record on vestibular schwannoma molecular profiling, which may eventually inform tumor subtype classification and management.+Save
PU¶PubMed·Journal article·Vestibular·8w agoWavelet-based assessment of postural stability in young female volleyball players using a baroresistive platformAdvances in posturography analysis methods — like wavelet-based assessments — may eventually refine vestibular function testing tools used in audiology and balance clinics.+Save
PU¶PubMed·Journal article·Vestibular·8w agoThe relationship between vertigo severity, psychiatric symptoms and obstructive sleep apnoeaAudiologists and vestibular specialists should be aware that vertigo severity in OSA patients may co-occur with psychiatric symptoms, but the cross-sectional design prevents causal conclusions and no immediate protocol change is warranted.+Save
PU¶PubMed·Journal article·Research (general)·8w agoNADPH oxidase 3 inhibition preserves hearing in mice after stereotactic radiosurgeryRadiation-induced hearing loss is a major quality-of-life burden for vestibular schwannoma patients, and identifying a targetable enzyme pathway could eventually lead to a pharmacological hearing-protection strategy during radiosurgery.+Save
PU¶PubMed·Journal article·Research (general)·8w agoPeripheral CD4 T-Cell State Remodeling in Migraine Revealed by Single-Cell RNA SequencingUnderstanding the neuroimmune basis of migraine may eventually inform treatment of vestibular migraine, a condition routinely encountered in audiology and otoneurology clinics.+Save
PU¶PubMed·Journal article·Vestibular·8w agoRecurrent brief positional vertigo as the initial presentation of medial branch of the posterior inferior cerebellar artery territory cerebellar infarction: a case reportAudiologists and vestibular specialists should maintain a low threshold for neurological referral when positional vertigo is recurrent and atypical (e.g., lacks classic BPPV features or canal-conversion patterns), as it can be the first sign of cerebellar stroke.+Save
PU✚PubMed·Clinical trial·Vestibular·8w agoVirtual Reality-Based Vestibular Rehabilitation for Vestibular Migraine: A Randomized TrialIf VR-augmented vestibular rehabilitation shows significantly better outcomes than home-based therapy alone, clinicians managing vestibular migraine patients should consider VR as an adjunct — but clinical adoption should await the full published results and effect-size...+Save
PU¶PubMed·Journal article·Vestibular·8w agoFacial Nerve Preservation in Hannover IV Vestibular Schwannomas. What Factors Can Predict Facial Outcome?Surgeons treating large (Hannover grade IV) vestibular schwannomas should note the predictive factors identified for facial nerve preservation, but the retrospective single-centre design limits immediate practice change; prospective validation is needed before altering surgical...+Save
PU¶PubMed·Journal article·Vestibular·8w agoBrainstem and cerebellar variations in cheetahs (Acinonyx jubatus)Identifying enlarged semicircular canals in cheetahs as an adaptation for high-speed stability advances comparative vestibulomotor research and may inspire biomechanical models of balance and gaze control.+Save
PU¶PubMed·Journal article·Vestibular·8w agoDoes CANVAS mimic MSA-C? A prospective multimodal studyAudiologists and vestibular specialists should be aware that CANVAS (with its vestibular areflexia) can present with features—like dysautonomia and parkinsonism—that mimic MSA-C, warranting consideration of RFC1 genetic testing in ambiguous cases before labeling a patient with...+Save
PU¶PubMed·Journal article·Vestibular·8w agoVestibular contributions adapt to the balance strategies adopted during incline and decline walkingNo immediate change to clinical vestibular rehabilitation protocols is warranted, but these findings refine the basic science understanding of vestibular-motor integration during sloped walking, which may eventually inform fall-prevention or rehab strategies.+Save
PU¶PubMed·Journal article·Vestibular·8w agoIsolated Vestibular Nucleus Infarction Presenting as Vestibular Pseudoneuritis Mimicking Acute Peripheral VestibulopathyIsolated vestibular nucleus infarction can be clinically indistinguishable from acute peripheral vestibulopathy; clinicians should maintain a low threshold for urgent neuroimaging (MRI) in patients presenting with sudden vestibular syndrome, particularly when vascular risk...+Save
PU¶PubMed·Journal article·Vestibular·8w agoTOEPVA: a systematic review and meta-analysis of safety, efficacy and feasibilityTOEPVA represents a scar-free surgical alternative for parathyroid disease, but its relevance to the audiology field is negligible unless monitoring post-surgical calcium levels that could affect neuromuscular hearing function.+Save
PU¶PubMed·Journal article·Vestibular·8w agoBaseline severity is not treatment timing in acute rimegepant treatment for vestibular migraineVestibular migraine is a common cause of episodic vertigo seen in audiology and neurotology clinics, and clarifying how treatment timing vs. baseline severity affects outcomes has real implications for clinical decision-making.+Save
PU¶PubMed·Journal article·Vestibular·8w agoLong-Term Nervus Intermedius Dysfunction After Retrosigmoid Vestibular Schwannoma Resection: Incidence, Independent Predictors, and Development of a NomogramAudiologists co-managing vestibular schwannoma patients post-surgery should be aware that nervus intermedius dysfunction (affecting taste and facial sensation) is a measurable long-term risk after retrosigmoid resection, and that the published nomogram may help identify...+Save
PU¶PubMed·Journal article·Vestibular·8w agoReply to: Baseline severity is not treatment timing in acute rimegepant treatment for vestibular migraineThe exchange highlights unresolved methodological questions about how to analyze acute vestibular migraine treatment trials, which matter for how audiologists and vestibular specialists interpret future rimegepant evidence.+Save
PU¶PubMed·Journal article·Vestibular·8w agoDisentangling sensory contributions to postural control regulation through sample entropy and neural modeling: A preliminary studyQuantifying the auditory contribution to postural control could refine vestibular rehabilitation protocols and inform how audiologists counsel patients with combined hearing and balance disorders.+Save
PU¶PubMed·Journal article·Vestibular·8w agoThe Effectiveness of Group-based Vestibular Rehabilitation in Adults With Central or Peripheral Vestibular Dysfunction: A Systematic ReviewAudiologists and vestibular rehabilitation providers should review this systematic review to determine whether group-based vestibular rehabilitation offers comparable outcomes to individual therapy, which could expand access and reduce cost in balance disorder management.+Save