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✦ The Dispatch

Vestibular schwannoma associated normal pressure hydrocephalus: clinical features and shunt responsiveness compared with idiopathic NPH

A dispatch from PubMed — filed

Vestibular schwannoma (VS) is commonly associated with obstructive hydrocephalus due to mass effect; however, a rarer communicating form resembling normal pressure hydrocephalus (NPH) has also been described, possibly related to impaired CSF absorption from elevated CSF protein....

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✦ The floor

Discussion

Signed responses from readers of the wire.

Clinical Takeaway

Audiologists should be aware that vestibular schwannoma patients can develop NPH, as this may influence referral pathways, but direct clinical practice change for audiology is limited — this is primarily a neurosurgical concern.

Why It Matters

Recognizing that vestibular schwannoma can trigger NPH expands the differential diagnosis for balance and cognitive symptoms in this patient population, with implications for neurotology referral and multidisciplinary care.

Key Points
  1. 01Vestibular schwannoma can be associated with normal pressure hydrocephalus (NPH), a brain fluid condition.
  2. 02Study retrospectively compared VS-associated NPH with idiopathic (unknown cause) NPH.
  3. 03Shunt responsiveness (how well the drainage tube worked) was compared between the two groups.
  4. 04Findings have implications for neurosurgical management of vestibular schwannoma patients.
  5. 05Retrospective design limits strength of conclusions.
Claims & Evidence

Vestibular schwannoma-associated NPH has distinct clinical features compared with idiopathic NPH.

studypartially supported

Shunt responsiveness differs between vestibular schwannoma-associated NPH and idiopathic NPH.

studyunclear
Research metadata
PMID
42623790
DOI
10.1016/j.jocn.2026.112253.
Journal
Journal of Clinical Neuroscience
Publication type
research_article
Evidence level
3
Population
Patients with vestibular schwannoma-associated normal pressure hydrocephalus and patients with idiopathic NPH
Intervention
CSF shunting for normal pressure hydrocephalus
Comparator
Idiopathic normal pressure hydrocephalus

Primary outcomes

Clinical features of VS-associated NPH vs idiopathic NPH; Shunt responsiveness in each group

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