✦ The floor
Discussion
Signed responses from readers of the wire.
✦ Clinical Takeaway ✦
No actionable change — this is a published correction to a molecular biology study and does not alter clinical practice.
✦ Why It Matters ✦
Correction notices maintain the integrity of the scientific record on vestibular schwannoma molecular profiling, which may eventually inform tumor subtype classification and management.
✦ Key Points ✦
- 01Correction notice only — no new data or findings are presented.
- 02Original study profiled gene expression across the whole transcriptome in cystic vs. solid vestibular schwannomas.
- 03Long non-coding RNAs (genetic material that regulates gene activity) were identified as candidate markers distinguishing tumor subtypes.
- 04Published in Molecular Biology Reports (2026).
- 05Cystic vestibular schwannomas are clinically distinct and tend to have worse surgical outcomes than solid ones.
✦ Research metadata ✦
- PMID
- 42622948
- DOI
- 10.1007/s11033-026-12606-z.
- Journal
- Molecular Biology Reports
- Publication type
- editorial
- Evidence level
- 4
- Population
- Patients with cystic and solid vestibular schwannomas
- Intervention
- Transcriptome-wide profiling (RNA sequencing) of vestibular schwannoma tissue
- Comparator
- Solid vestibular schwannomas vs. cystic vestibular schwannomas
Primary outcomes
Identification of long non-coding RNA expression signatures differentiating cystic from solid vestibular schwannomas