Hearing Review·Press release·Research (general)·2w agoSensorion Names SENS-601 Lead Gene Therapy Program, Files Clinical Trial Applications for GJB2-Related Hearing LossGJB2 mutations are the most frequent genetic cause of congenital deafness, so a successful AAV gene therapy could eventually offer a biological treatment option for a large portion of patients with hereditary hearing loss.＋Save
RNID·Other·Research (general)·2w agoDeveloping gene therapy for TOMT-linked hearing lossTOMT-linked hearing loss is a distinct genetic subtype, and targeted gene therapies for specific mutations represent the frontier of curative audiology research.＋Save
RNID·Other·Research (general)·3w agoInvestigating the feasibility of gene therapy for stereocilin-related hearing lossStereocilin mutations cause a specific inherited form of hearing loss, and a successful gene therapy could one day offer a curative option beyond hearing aids or cochlear implants.＋Save
RNID·Other·Hearing aids·3w agoEvaluating a novel signal-processing strategy for improving perception of speechA successful new signal-processing strategy for noisy environments would directly address one of the most common and persistent complaints of hearing-aid users, potentially improving device satisfaction and uptake.＋Save
RNID·Other·Tinnitus·3w agoDisentangling brain activity underlying hyperacusis and tinnitusIdentifying distinct brain-level mechanisms for hyperacusis versus tinnitus could pave the way for condition-specific diagnostic tools and therapies, which are currently lacking.＋Save
RNID·Other·Research (general)·3w agoReal-time monitoring of listening effort and fatigue in older adultsValidated real-world measures of listening effort and fatigue could fill a major gap in audiological assessment, enabling more person-centred rehabilitation for older adults.＋Save
PU¶PubMed·Journal article·Research (general)·3w agoInterplay of age, speech perception in noise, standard and extended high-frequency hearing, and cochlear synaptopathy in individuals with normal audiogramsExtended high-frequency audiometry and cochlear synaptopathy measures may help explain speech-in-noise difficulties in patients with normal standard audiograms, but routine clinical adoption requires further validation before practice change is warranted.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoEvaluation of Cochlear Function, Hidden Hearing Loss, and Auditory Temporal Processing in Tinnitus Patients with Normal AudiogramsHidden hearing loss and auditory temporal processing measures may reveal underlying dysfunction in tinnitus patients with normal audiograms, but findings need replication in larger controlled trials before changing clinical evaluation protocols.＋Save
PU¶PubMed·Journal article·Vestibular·3w agoIntraoperative High Resolution 2D and 3D Angiography in Cervical Decompression for Sub-Axial Bow Hunter's SyndromeBow Hunter's Syndrome can mimic inner ear disorders, so audiologists and neurotologists should be aware of this rare vascular diagnosis when patients report position-dependent dizziness or sudden auditory symptoms.＋Save
PU¶PubMed·Journal article·Cochlear implants·3w agoRobotic-Assisted Electrode Insertion for Pediatric Cochlear Implantation: A Multicenter StudyRobotic-assisted electrode insertion appears safe and feasible in pediatric cochlear implantation across multiple centers, but the small sample (n=14) and absence of long-term audiological outcome data mean it is too early to recommend over standard manual insertion.＋Save
PU¶PubMed·Journal article·Vestibular·3w agoNeurological complications in microgravity and long duration spaceflightSpaceflight-induced neuro-otological changes — including vestibular and possibly auditory pathway alterations — may offer extreme-environment insights relevant to understanding balance and hearing disorders more broadly.＋Save
PU¶PubMed·Journal article·Vestibular·3w agoInternet-based vestibular rehabilitation versus written instructions after acute vertigo: A randomised controlled trialIf internet-based vestibular rehabilitation proves superior to written instructions, clinicians treating acute vestibular syndrome in emergency settings should consider recommending structured online rehab programs as a first-line follow-up resource — pending full review of the...＋Save
PU¶PubMed·Journal article·Vestibular·3w agoTumor-to-Tumor Metastasis Involving Vestibular Schwannoma: Case Report and Literature ReviewTumor-to-tumor metastasis involving vestibular schwannoma is exceedingly rare, and awareness of this entity may prevent misdiagnosis and guide appropriate pathologic evaluation in atypical cases.＋Save
PU¶PubMed·Journal article·Public health & policy·3w agoA Systematic Review and Quality Assessment of Clinical Practice Guidelines for Otitis Externa to Support the WHO Package of Ear and Hearing Care InterventionsClinicians should cross-reference their local otitis externa protocols with the WHO-aligned best-practice recommendations identified in this review, particularly in settings where formal guidelines may be absent or outdated.＋Save
PU¶PubMed·Journal article·Cochlear implants·3w agoBaseline Function Predicts Gains in Both Speech Recognition and Quality of Life After Cochlear ImplantationPre-implant baseline speech recognition and quality-of-life scores should be routinely documented, as they are significant predictors of post-implantation outcomes and can guide patient counselling and candidacy decisions.＋Save
PU¶PubMed·Journal article·Cochlear implants·3w agoA modified hook-assisted transmuscular technique to optimise cochlear implant coupling in patients with thick scalp flapsSurgeons performing cochlear implantation in patients with thick scalp flaps (>8 mm) may consider this hook-assisted transmuscular technique as a practical option to optimise magnet coupling and signal transmission, pending broader replication.＋Save
PU¶PubMed·Journal article·Clinical audiology·3w agoNeuroendocrine Tumor of the Middle EarClinicians evaluating unexplained middle ear masses should include MEANT in the differential diagnosis; definitive diagnosis requires histopathology with neuroendocrine markers, and this case adds to a limited literature—no practice change is warranted beyond diagnostic...＋Save
PU¶PubMed·Journal article·Research (general)·3w agoCharacterizing sexual dysfunction in females with hypermobile Ehlers Danlos syndrome or hypermobility spectrum disorder and genito-pelvic pain through cross-sectional analysisThis article does not have meaningful relevance to the audiology field; it addresses sexual dysfunction in a connective tissue disorder population without a hearing-related focus.＋Save
PU¶PubMed·Journal article·Research (general)·3w agoCalcitonin Gene-Related Peptide (CGRP): Biology, Signaling, Pathophysiological Roles, and Therapeutic ApplicationsUnderstanding CGRP's role in the auditory and vestibular systems may open future therapeutic targets for conditions such as vestibular migraine and Ménière's disease.＋Save
PU¶PubMed·Journal article·Vestibular·3w agoBalance Disorders: Insufficient Supply of Vestibular Examinations by the Italian National Health Service, 2021-2023Quantifying the gap between need and supply of vestibular testing highlights a systemic healthcare access problem that may mirror shortfalls in other national health systems globally.＋Save
PU¶PubMed·Journal article·Vestibular·3w agoPersistent Dizziness and Time-Domain Dissociation in Vestibular Function: A Hypothesis-Generating Case Series and Spatiotemporal Framework for Targeted Vestibular RehabilitationThis is hypothesis-generating only; the spatiotemporal framework is not yet validated, so no change to vestibular rehabilitation protocols is warranted until prospective studies confirm the model.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoEmpowerment, Self-Management and Illness Perception of Users of an Online Self-Help Platform for Tinnitus: A Cross-Sectional StudyOnline self-help platforms may support empowerment and self-management in tinnitus patients, but this cross-sectional design cannot establish cause-and-effect; audiologists should consider digital support tools as a complement to, not replacement for, structured tinnitus...＋Save
PU¶PubMed·Journal article·Cochlear implants·3w agoContinuous vs. Interrupted Multi-Talker Babble Background Noise: Impact on Speech Perception in Bimodal Cochlear ImplantsAudiologists fitting bimodal cochlear implant users should consider including both continuous and interrupted background noise conditions in speech-perception testing, as these may capture different aspects of real-world listening performance relevant to candidacy and outcome...＋Save
PU¶PubMed·Journal article·Clinical audiology·3w agoWideband Tympanometry Findings in Otitis Media with Effusion-A Systematic ReviewWideband tympanometry shows promise as a more sensitive diagnostic tool for otitis media with effusion in children than conventional tympanometry, but routine protocol adoption should await further standardization of reference norms.＋Save
PU¶PubMed·Journal article·Vestibular·3w agoSkull Pneumatization Forms a Biothermal System Protecting Ocular and Vestibular HomeostasisIf validated, this novel biothermal hypothesis could offer a new framework for understanding why some patients develop vestibular or ocular symptoms linked to middle ear and sinus pathology.＋Save
PU¶PubMed·Journal article·Research (general)·3w agoThe Genetic Causes of Auditory Neuropathy: A Systematic ReviewGenetic testing for auditory neuropathy is clinically meaningful because the causative gene can influence cochlear implant candidacy and expected outcomes; audiologists should advocate for genetic workup in confirmed auditory neuropathy cases.＋Save
PU¶PubMed·Journal article·Cochlear implants·3w agoAuditory Performance Analysis and Evaluation of Quality of Life After Cochlear Implantation in Patients Aged 60 (Sixty) and OlderCochlear implantation delivers meaningful auditory and quality-of-life gains in patients aged 60+; age alone should not be a barrier to implant candidacy, though pre-operative factors such as duration of deafness and residual speech recognition matter.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoAssociations of Dietary Factors, Body Mass Index, and Physical Activity with Tinnitus: A Scoping ReviewCurrent evidence is insufficient to recommend specific dietary or lifestyle interventions for tinnitus management; however, the review supports discussing general metabolic health and physical activity as part of holistic patient counseling.＋Save
PU¶PubMed·Journal article·Research (general)·3w agoNetwork Meta-Analysis of Cognitive Impairment and miRNA Expression in Alzheimer's Disease Patients with Hearing Loss: A Systematic Review and Cross-ValidationClarifying the molecular link between hearing loss and Alzheimer's disease could eventually guide early screening and intervention strategies in audiology practice.＋Save
