PU¶PubMed·Journal article·Vestibular·2w agoCSNK1A1 Mediates Inner Ear Inflammation and Endolymphatic Hydrops in a Lipopolysaccharide-Induced Mouse ModelIdentifying CSNK1A1 as a mediator of inner ear inflammation and endolymphatic hydrops opens a new molecular target pathway for potential Meniere's disease treatments.
PU¶PubMed·Journal article·Vestibular·5w agoResearch progress on the mechanisms and animal models of Ménière's diseaseA comprehensive review of Ménière's disease mechanisms and animal models provides a research roadmap that could accelerate development of targeted therapies for this poorly understood and difficult-to-treat condition.＋Save
PU¶PubMed·Journal article·Vestibular·6w agoBurden of novel and ultra-rare missense variants in the NF-κB pathway genes associated to Ménière's diseaseIdentifying an immune-genetic basis for Ménière's disease could open new therapeutic targets and improve patient stratification, which is significant given the condition's poorly understood aetiology.＋Save
PU¶PubMed·Journal article·Vestibular·7w agoAssociation Between the Fukuda Stepping Test and Foulage Test Parameters in Healthy Adults and Patients With Ménière's DiseaseIf the Fukuda Stepping Test and Foulage Test show meaningful correlation in Ménière's patients, the simpler Fukuda test may serve as a low-cost proxy for platform-based balance assessment, but clinicians should await broader validation before replacing current protocols.＋Save
PU¶PubMed·Journal article·Vestibular·8w agoCharacterizing nystagmus using a portable eye movement recorder in patients with Meniere's disease and MRI-confirmed endolymphatic hydropsPortable eye-movement recording may help characterize nystagmus direction during Meniere's attacks and correlate it with MRI-confirmed hydrops, but the study is preliminary and does not yet support a change in routine clinical diagnostic practice.＋Save
