PU¶PubMed·Journal article·Vestibular·1d agoPhoton-counting CT based vestibular aqueduct trajectory analysis for the assessment of Meniere's disease endotypes and hearing lossPhoton-counting CT vestibular aqueduct trajectory analysis shows promise for sub-typing Ménière's disease, but clinical adoption requires validation in larger prospective cohorts before it should change imaging or diagnostic practice.
PU¶PubMed·Journal article·Vestibular·1d agoInflammatory and immune pathways in Ménière's disease: a multi-database bibliometric and visualized analysis of research trendsMapping the growth and direction of immune/inflammatory research in Ménière's disease helps researchers identify gaps and prioritise future investigations into the disease's underlying causes.＋Save
PU¶PubMed·Journal article·AI & technology·5w agoHuman-AI collaboration using GPT-5 for MR grading of endolymphatic hydrops in Ménière's diseaseFindings are preliminary for clinical adoption; audiologists and ENT teams should monitor this space, but no change to current MRI reporting or Ménière's disease diagnostic workflows is warranted yet.＋Save
PU¶PubMed·Journal article·Vestibular·7w agoGenetic contributions to familial Ménière's disease: a systematic reviewIdentifying hereditary genetic variants linked to Ménière's disease could eventually enable earlier diagnosis and targeted treatment for the subset of patients with a familial form of the condition.＋Save
PU¶PubMed·Journal article·Vestibular·3mo agoCSNK1A1 Mediates Inner Ear Inflammation and Endolymphatic Hydrops in a Lipopolysaccharide-Induced Mouse ModelIdentifying CSNK1A1 as a mediator of inner ear inflammation and endolymphatic hydrops opens a new molecular target pathway for potential Meniere's disease treatments.＋Save
PU¶PubMed·Journal article·Vestibular·4mo agoResearch progress on the mechanisms and animal models of Ménière's diseaseA comprehensive review of Ménière's disease mechanisms and animal models provides a research roadmap that could accelerate development of targeted therapies for this poorly understood and difficult-to-treat condition.＋Save
PU¶PubMed·Journal article·Vestibular·4mo agoBurden of novel and ultra-rare missense variants in the NF-κB pathway genes associated to Ménière's diseaseIdentifying an immune-genetic basis for Ménière's disease could open new therapeutic targets and improve patient stratification, which is significant given the condition's poorly understood aetiology.＋Save
PU¶PubMed·Journal article·Vestibular·4mo agoAssociation Between the Fukuda Stepping Test and Foulage Test Parameters in Healthy Adults and Patients With Ménière's DiseaseIf the Fukuda Stepping Test and Foulage Test show meaningful correlation in Ménière's patients, the simpler Fukuda test may serve as a low-cost proxy for platform-based balance assessment, but clinicians should await broader validation before replacing current protocols.＋Save
PU¶PubMed·Journal article·Vestibular·4mo agoCharacterizing nystagmus using a portable eye movement recorder in patients with Meniere's disease and MRI-confirmed endolymphatic hydropsPortable eye-movement recording may help characterize nystagmus direction during Meniere's attacks and correlate it with MRI-confirmed hydrops, but the study is preliminary and does not yet support a change in routine clinical diagnostic practice.＋Save
