Characterizing nystagmus using a portable eye movement recorder in patients with Meniere's disease and MRI-confirmed endolymphatic hydrops

Meniere's disease (MD) causes episodic vertigo and fluctuating hearing loss. During attacks, nystagmus may appear either toward (i.e., irritative) or away from (i.e., paralytic) the affected ear, but it is difficult to observe these patterns in real-time....

Portable eye-movement recording may help characterize nystagmus direction during Meniere's attacks and correlate it with MRI-confirmed hydrops, but the study is preliminary and does not yet support a change in routine clinical diagnostic practice.

Linking portable, real-world nystagmus characterization to MRI-confirmed endolymphatic hydrops could advance objective, accessible vestibular diagnostics for Meniere's disease.

1. 01Portable eye-movement recorder used to capture nystagmus patterns during Meniere's disease attacks.
2. 02All participants had MRI-confirmed endolymphatic hydrops, providing objective disease verification.
3. 03Study distinguished between irritative (excitatory) and other nystagmus directions during acute episodes.
4. 04Findings may improve understanding of inner-ear physiology during Meniere's attacks.
5. 05Portable design suggests potential for out-of-clinic or ambulatory vestibular monitoring.

PMID

42160796

DOI

10.1016/j.anl.2026.04.005.

Journal

Auris Nasus Larynx

Publication type

research_article

Evidence level

4

Population

Patients with Meniere's disease and MRI-confirmed endolymphatic hydrops experiencing acute vestibular attacks with nystagmus

Intervention

Portable eye-movement recorder to characterize nystagmus during Meniere's disease attacks