Audiology News

PubMed·Journal article·Research (general)·6w ago

Structural basis of ligand recognition and gating in a heteromeric Deg-3/Des-2 nicotinic acetylcholine receptor

Understanding the structural and evolutionary basis of nicotinic acetylcholine receptor gating could, in the long run, inform drug design targeting auditory hair-cell or efferent-pathway receptors, though that application is currently speculative.

Live dispatches

✦ This month

Cnidarian mechanosensory cells as ancestors of vertebrate hair cells: Molecular targeting of an ancient mechanotransduction complex

Live dispatches

Live dispatches

✦ This month

Cnidarian mechanosensory cells as ancestors of vertebrate hair cells: Molecular targeting of an ancient mechanotransduction complex

Longitudinal adaptations in neural and behavioral systems following hearing restoration using cochlear implants

✦ Past 90 days

Structural basis of ligand recognition and gating in a heteromeric Deg-3/Des-2 nicotinic acetylcholine receptor

Selective saccular plasticity under microgravity links peripheral transcriptomic remodeling to postflight vestibular dysfunction

✦ Earlier

Morphological and functional diversity of spatially resolved vestibular ganglion neuron cell types

Type I hair cells of striolar and central zones in vestibular organs are essential for head stability and postural control

Aging increases the cortical resources allocated to static balance maintenance

A hemispheric decoding principle for vestibular heading perception in the posterior sylvian area

Regulation of Tmem30b-mediated apical membrane homeostasis in auditory outer hair cells is critical for hearing