PU¶PubMed·Preprint·Vestibular·5w agoMerlin restoration prevents schwannoma progression in a genetically engineered mouse model of NF2 -SWNIdentifying Merlin restoration as a potential therapeutic strategy for vestibular schwannoma progression could open new treatment avenues for a condition that currently has limited non-surgical options.
PU¶PubMed·Journal article·Vestibular·2mo agoManagement strategies for vestibular schwannomas in patients with NF2-related schwannomatosis: a systematic reviewA synthesis of management strategies for this rare but devastating condition helps neurotology and audiology teams weigh surgery, radiation, observation, and emerging medical therapies for a patient population with very limited options.＋Save
PU¶PubMed·Journal article·Research (general)·4mo agoDeterminants of the quality of life of patients with NF2-related schwannomatosis and validation of the Dutch NFTI-QOL questionnaireNo immediate change to audiological practice; the validated Dutch NFTI-QOL questionnaire is now available for use in Dutch-speaking NF2 patient populations to better capture quality-of-life data in clinical and research settings.＋Save
PU¶PubMed·Journal article·Clinical audiology·4mo agoGiant skull base collision tumors in NF2-related schwannomatosis: longitudinal outcomes of planned selective resectionPlanned selective (partial) resection may be a viable long-term strategy for giant skull base collision tumors in NF2-related schwannomatosis, but this is a specialized neurosurgical finding; audiologists managing these patients should be aware of the surgical philosophy but no...＋Save
