PU¶PubMed·Journal article·Tinnitus·2w agoCase Report: Repeated courses of low-frequency rTMS for refractory tinnitus: an N-of-1 studyRefractory tinnitus remains one of audiology's hardest therapeutic challenges, and this report adds a data point on whether repeated rTMS courses sustain benefit, though far larger trials are needed.＋Save
PU¶PubMed·Journal article·Cochlear implants·2w agoA Nordic cohort study on cochlear implants and binaural hearing in single-sided deafnessCohort-level outcomes data from a Nordic population support cochlear implantation as a treatment option for adult single-sided deafness, reinforcing existing evidence — audiologists should review specific outcome metrics once the full paper is available to refine candidacy...＋Save
PU¶PubMed·Journal article·Vestibular·2w agoZDHHC5 may regulate the function of NKT cells and the immune response in Meniere's diseaseIdentifying a genetic regulator of immune activity in Ménière's disease advances the understanding of its poorly characterized autoimmune mechanisms, potentially opening new therapeutic targets.＋Save
PU¶PubMed·Journal article·Tinnitus·2w agoTargeted inhibition of the BDNF/AKT/mTOR pathway in the inferior colliculus ameliorates salicylate-induced tinnitus in ratsIdentifying the BDNF/AKT/mTOR pathway as a contributor to tinnitus opens a new molecular target avenue that could eventually lead to the first pharmacological treatments for tinnitus in humans.＋Save
PU¶PubMed·Journal article·Tinnitus·2w agoAudiologic Characteristics of Military Service Members and Veterans With and Without Tinnitus and Comorbid Posttraumatic Stress DisorderAudiologists working with military and veteran populations should be aware that comorbid PTSD may be associated with distinct audiologic profiles in tinnitus patients, suggesting the need for integrated screening and interdisciplinary care pathways.＋Save
PU¶PubMed·Journal article·Tinnitus·2w agoClinical and Demographic Characterization of Tinnitus and Factors Associated With Discomfort in a Large Sample of Patients Evaluated in Bogota, ColombiaClinicians in Latin American settings and globally may reference this large-sample characterization to benchmark local tinnitus populations, though findings must be replicated before changing assessment or management protocols.＋Save
PU¶PubMed·Journal article·Tinnitus·2w agoPsychological Correlates of Tinnitus Handicap: Associations with Personality Traits and Emotional DistressAudiologists managing tinnitus patients should routinely screen for emotional distress and personality-linked vulnerability, as these psychological factors appear to independently predict tinnitus-related handicap and may warrant referral for psychological support.＋Save
PU¶PubMed·Journal article·Research (general)·2w agoNeurovascular-Immune Biomarkers in Ménière Disease: Insights From High-Throughput ProteomicsIdentifying reliable biomarkers for Ménière disease could eventually enable objective diagnosis and targeted therapies for a condition currently managed by symptom control alone.＋Save
PU¶PubMed·Journal article·Research (general)·2w agoSynaptic zinc plasticity shapes adaptive and maladaptive cortical plasticity following cochlear injuryIdentifying synaptic zinc plasticity as a driver of both adaptive and maladaptive auditory cortex reorganization after cochlear injury opens a potential new molecular target for future tinnitus and hearing-loss therapies.＋Save
PU¶PubMed·Journal article·Tinnitus·2w agoInvestigation of Hyperacusis in Patients with TinnitusAudiologists managing tinnitus patients should routinely screen for hyperacusis, as this study suggests meaningful co-occurrence; however, practice protocols should await replication in larger, well-controlled studies.＋Save
RNID·Blog·Public health & policy·3w agoDon’t Lose the MusicMusic-induced noise exposure is a preventable and under-addressed cause of hearing loss, and public advocacy content from organisations like RNID can support audiologists' patient education efforts.＋Save
PU¶PubMed·Journal article·Research (general)·3w agoIn-Ear Transcranial Alternating Current Stimulation: Auditory Perception and Side Effects Depend on Electrode Montage, Frequency, and Direct Current-OffsetUnderstanding how electrode placement, frequency, and DC-offset shape both the perceptual and safety profile of in-ear tACS is a necessary step toward developing cochlear neuromodulation as a potential tinnitus or hearing rehabilitation therapy.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoInflammatory Signatures of Tinnitus in Patients and MiceIdentifying specific inflammatory markers shared across human tinnitus patients and animal models opens a credible biological pathway for future drug or immunotherapy targets, potentially reshaping how tinnitus is treated.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoEEG microstates and dynamic functional connectivity reveal stage-specific brain networks in subjective tinnitusIdentifying stage-specific brain network signatures in tinnitus could eventually guide targeted neurostimulation or biofeedback therapies, moving tinnitus management beyond symptom masking.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoMedial Geniculate Body Deep Brain Stimulation for Refractory Tinnitus: Neurophysiological Rationale and Translational Neuromodulation PerspectivesFor the estimated millions with treatment-refractory tinnitus, a neurophysiologically grounded neuromodulation target could open an entirely new category of intervention if translational research advances.＋Save
Hearing Practitioner Australia·Journal article·Public health & policy·3w agoHearing loss, tinnitus appear earlier and are more severe in veterans, study findsAudiologists seeing veteran patients should anticipate earlier onset and greater severity of both hearing loss and tinnitus compared to civilian norms, and may need to adjust screening thresholds and rehabilitation planning accordingly for this population.＋Save
Hearing Health Matters·Press release·Tinnitus·3w agoSonorous Neurovascular Enrolls First Canadian Patient in B-SILENT Pulsatile Tinnitus StudyPulsatile tinnitus linked to narrowed brain blood vessels (cerebral venous sinus stenosis) has very limited treatment options, and a dedicated implant trial could open a new interventional pathway if results are positive.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoAuthor Reply to Letter to the Editor Regarding "Intratympanic Dexamethasone Efficacy in Preventing Cisplatin-Induced Tinnitus: A Randomized Controlled Phase IIIB Clinical Trial"This is an author reply to a letter to the editor and does not introduce new data; no change to current practice is warranted until the full exchange is evaluated in context of the original Phase IIIB trial findings.＋Save
PU¶PubMed·Journal article·Research (general)·3w agoAssociation between hearing loss, tinnitus, and atherosclerotic cardiovascular disease among American adults: A cross-sectional studyAudiologists should be aware of the association between hearing loss/tinnitus and cardiovascular disease risk, and consider flagging patients with hearing symptoms for cardiovascular screening referral — though this cross-sectional design cannot confirm cause and effect.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoNeural Indicators of Inhibition in Tinnitus: Onset-Offset and Sensory Gating Auditory Evoked Potentials Vary by Stimulus Frequency and Tinnitus SeverityOnset-offset and sensory gating evoked potentials show promise as objective neural markers of inhibitory dysfunction in tinnitus, but findings are preliminary; no direct change to clinical assessment protocols is warranted yet.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoNetwork analysis of the tinnitus functional index (TFI)Network analysis findings may inform refinement of TFI subscale interpretation, but clinicians should continue using the validated full TFI without modification until revised scoring guidelines are published.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoLetter to the editor re: Sathya A, Nguyen TN, Klein P, et al. Endovascular vs surgical treatment of sigmoid sinus diverticulum causing pulsatile tinnitus: A systematic review. Interv Neuroradiol. 2024 Mar 22:15910199241231325Critical appraisal of systematic reviews on pulsatile tinnitus treatments helps refine the evidence base for a condition that is often underdiagnosed and mismanaged.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoMethodological considerations in the UK Biobank diabetes-tinnitus studyRigorous methodological critique of large database studies on tinnitus is important as flawed observational designs can lead to misleading clinical guidance in a field that already has limited evidence-based treatments.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoDeep brain stimulation of the medial geniculate body for refractory tinnitus: a 2 year follow-upToo preliminary (single case or very small series) to justify any change in clinical practice; deep brain stimulation for tinnitus remains experimental.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoVitamin D receptor rs2228570 (FokI) variant is associated with chronic tinnitus susceptibilityIdentifying a genetic susceptibility marker for chronic tinnitus opens a potential pathway toward understanding its biological mechanisms and, eventually, targeted prevention or treatment strategies.＋Save
PU¶PubMed·Journal article·Tinnitus·3w agoFour decades of tinnitus pathology research: a bibliometric analysis of scientific trends, collaborations, and research hotspotsUnderstanding four decades of tinnitus research trends helps guide where future funding, international collaboration, and clinical investigation should be directed.＋Save
PU¶PubMed·Journal article·Tinnitus·4w agoRe: "Intratympanic Dexamethasone Efficacy in Preventing Cisplatin-Induced Tinnitus: A Randomized Controlled Phase IIIb Clinical Trial" by Moreno and BelinchonClinicians should read both the original Phase IIIb RCT and this correspondence carefully before adopting intratympanic dexamethasone as a routine protocol for preventing cisplatin-induced tinnitus, as the letter may highlight methodological or interpretive concerns.＋Save
PU¶PubMed·Journal article·Cochlear implants·4w agoTinnitus outcomes after unilateral and bilateral cochlear implantationAudiologists and cochlear implant teams should review this study when counselling implant candidates about tinnitus expectations; if bilateral implantation shows meaningfully greater tinnitus suppression, it may strengthen candidacy arguments for bilateral procedures in patients...＋Save
PU¶PubMed·Journal article·Tinnitus·4w agoARISE II Consensus on Venous Sinus StentingAudiologists identifying patients with pulsatile tinnitus should ensure prompt medical referral for vascular and neuroimaging workup, as this consensus document elevates venous sinus stenosis as the leading treatable cause — strengthening the case for a structured referral...＋Save
