/OBJECTIVES: Cisplatin-exposed pediatric cancer patients are at increased risk of ototoxicity, particularly those under 5 years of age. In this group, audiological monitoring is challenging, as interpretation of otoacoustic emissions (OAEs) and tympanometry, used to supplement behavioral audiometry, is subject to interindividual variability....
Audiologists monitoring pediatric oncology patients on cisplatin should consider OAE screening protocols adapted to the practical challenges of testing children under 5, though specific protocol changes depend on the study's detailed findings and local resources.
Early detection of cisplatin-related hearing damage in very young children is critical for timely intervention, and validated age-appropriate screening protocols are a key clinical gap.
- 01Study targets children under 5 receiving cisplatin chemotherapy — a high-risk group for ototoxicity (drug-related hearing loss).
- 02Otoacoustic emissions (OAE) testing is evaluated as a feasible screening tool in this challenging age group.
- 03Practical and developmental barriers to audiological testing in young children are identified and addressed.
- 04Findings have direct relevance to pediatric oncology audiology programs.
- 05Early hearing monitoring in this group can inform intervention decisions before significant hearing loss occurs.
Otoacoustic emission screening is a feasible audiological testing method for children under 5 at risk of cisplatin-related ototoxicity.
studypartially supportedCisplatin chemotherapy poses an ototoxicity risk in pediatric patients requiring dedicated audiological monitoring strategies.
guidelinesupported- PMID
- 42201128
- DOI
- 10.3390/audiolres16030074.
- Journal
- Audiology Research
- Publication type
- research_article
- Evidence level
- 4
- Population
- Children under 5 years of age undergoing cisplatin chemotherapy with ototoxicity risk
- Intervention
- Otoacoustic emission (OAE) hearing screening
Primary outcomes
Feasibility of OAE screening in children under 5 with cisplatin-related ototoxicity risk; Identification of barriers to audiological testing in this age group