PU¶PubMed·Preprint·Vestibular·6d agoDisruption of a structural niche for otoconia maintenance may underlie common vestibular disordersIf confirmed, identifying a structural maintenance niche for otoconia could open new therapeutic targets for age-related vestibular disorders, which are among the most common causes of falls in older adults.
PU¶PubMed·Preprint·Research (general)·6d agoA comparative single-cell transcriptomic atlas for diverse populations of vertebrate hair cellsUnderstanding the genetic blueprint of hair cell diversity and regeneration across species could accelerate the search for strategies to restore hearing in humans.＋Save
PU¶PubMed·Preprint·Tinnitus·6d agoValidating the Gap-Startle Paradigm for Tinnitus Detection: A Machine Learning Approach in CBA/CaJ MiceImproving the accuracy and reliability of animal tinnitus detection models is an important step toward developing and validating future tinnitus therapies.＋Save
PU¶PubMed·Preprint·Vestibular·13d agoMerlin restoration prevents schwannoma progression in a genetically engineered mouse model of NF2 -SWNIdentifying Merlin restoration as a potential therapeutic strategy for vestibular schwannoma progression could open new treatment avenues for a condition that currently has limited non-surgical options.＋Save
PU¶PubMed·Preprint·Clinical audiology·13d agoDistinct Roles of Working Memory and Inhibitory Control in Speech-in-Noise PerceptionFindings support considering cognitive screening alongside audiometric testing for patients with real-world hearing complaints but normal thresholds, though clinical protocols should await peer-reviewed replication.＋Save
PU¶PubMed·Preprint·Vestibular·2mo agoHydrostatic pressure shapes and canalizes semicircular canal morphology to ensure vestibular functionUnderstanding the mechanical forces that govern vestibular organ development could eventually inform research into congenital vestibular malformations and related balance disorders.＋Save
PU¶PubMed·Preprint·Research (general)·2mo agoBouncing back: Transient, but not long-lasting, effects of background disturbances on speech processingDistinguishing transient from lasting effects of background noise on speech processing sharpens our understanding of listening effort and fatigue, with potential implications for hearing aid design and auditory rehabilitation counselling.＋Save
PU¶PubMed·Preprint·Research (general)·2mo agoArticulatory timing and form support distinct neural benefits during audiovisual speechIdentifying which components of visible speech (timing vs. shape) provide distinct neural benefits could improve the design of audiovisual training programmes and speechreading therapy for people with hearing loss.＋Save
PU¶PubMed·Preprint·Cochlear implants·2mo agoRevisiting Analog Electrical Stimulation with Current Focusing in a Guinea Pig Model of Cochlear ImplantsRevisiting analog stimulation with modern current-focusing approaches could open new paths to improving the spectral resolution that remains the central unmet need in cochlear implant users.＋Save
PU¶PubMed·Preprint·Research (general)·2mo agoStructural connectivity of auditory-linguistic brain networks predicts success in speech categorization and listening in noiseUnderstanding how structural brain connectivity underlies individual differences in speech-in-noise performance could eventually guide personalized hearing rehabilitation strategies.＋Save
PU¶PubMed·Preprint·Research (general)·2mo agoNeurophysiological Evidence for Reduced Use of Prior Sound Patterns to Shape Speech Processing in AutismUnderstanding why speech perception differs in autism at a brain-processing level could eventually guide more tailored auditory rehabilitation and communication support strategies for autistic individuals.＋Save
PU¶PubMed·Preprint·Research (general)·2mo agoOlder adults show overexaggerated and larger noise-related degradation in their neural tracking of speechThis finding suggests age-related declines in how the brain tracks speech in noise go beyond peripheral hearing loss; audiologists should be cautious attributing all speech-in-noise difficulty in older adults to the audiogram alone, though the preprint has not yet been...＋Save
PU¶PubMed·Preprint·Research (general)·2mo agoPerceptual consistency in phoneme categorization is driven by neural consistency and predicts improved speech-in-noise performanceNeural consistency in phoneme (speech-sound) processing may be a useful biomarker for predicting real-world speech-in-noise performance, but this preprint requires peer review before it can inform clinical assessment tools.＋Save
PU¶PubMed·Preprint·Cochlear implants·2mo agoWithin-electrode temporal envelope processing predicts multi-channel speech outcomes across cochlear implant pulse ratesWithin-electrode temporal envelope processing may serve as a clinically useful predictor of multi-channel speech outcomes in CI users across pulse rates; if replicated in peer-reviewed work, it could inform CI fitting strategies, but the preprint stage warrants caution before...＋Save
PU¶PubMed·Preprint·Vestibular·4mo agoAutism associated Cntnap2 deletion disrupts vestibular sensory signaling and spatial cognition in miceIf vestibular dysfunction is a reproducible feature of Cntnap2-related autism models, it opens a new biological pathway connecting autism genetics to inner-ear sensory processing that audiology and vestibular researchers should monitor.＋Save
PU¶PubMed·Preprint·Research (general)·5mo agoModulation statistics allow robust prediction of speech recognition accuracy across many words, voices, and natural background soundsThis preprint offers a potentially valuable acoustic framework for predicting speech-in-noise performance, but findings require peer review and clinical validation before influencing hearing aid fitting or speech-in-noise test selection.＋Save
PU¶PubMed·Preprint·Research (general)·5mo agoPrediction from Statistical Learning Aids Auditory Scene AnalysisUnderstanding how statistical learning and predictive processing shape auditory scene analysis could eventually guide the design of smarter hearing aids and auditory training programs.＋Save
