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Central Vestibular Syndromes

A dispatch from PubMed — filed

Although peripheral vestibular disorders account for the most cases of dizziness or vertigo, approximately 11-15% of patients have central vestibulopathy. This remains a diagnostic challenge for neurotologists, as it can present with acute vestibular syndrome (AVS) in isolation without other obvious neurologic deficits....

Clinical Takeaway

Clinicians should maintain awareness that 11–15% of dizziness presentations may have a central (brain-based) cause; however, this review does not introduce new diagnostic criteria or protocols that would change existing assessment workflows.

Why It Matters

Misdiagnosing central vestibular syndromes as peripheral can delay life-threatening diagnoses such as stroke, making accurate differentiation a critical clinical skill for audiologists and ENT teams.

Key Points
  1. 01Approximately 11–15% of dizziness/vertigo patients are estimated to have a central vestibular cause.
  2. 02Central vestibular syndromes arise from pathology in the brain (brainstem, cerebellum, cortex) rather than the inner ear.
  3. 03Distinguishing central from peripheral vestibular disorders remains a significant diagnostic challenge.
  4. 04Narrative review format synthesises existing literature rather than presenting new primary data.
  5. 05Published in Clinical and Experimental Otorhinolaryngology.
Claims & Evidence

Approximately 11–15% of patients presenting with dizziness or vertigo have central vestibulopathy.

studypartially supported

Central vestibular syndromes pose significant diagnostic challenges in clinical settings.

opinionsupported
Research metadata
PMID
42438433
DOI
10.21053/ceo.2026-00155.
Journal
Clinical and Experimental Otorhinolaryngology
Publication type
review
Evidence level
5
Population
Patients presenting with dizziness or vertigo (literature-based; no primary patient cohort)
Intervention
Narrative review of central vestibular syndrome classification and diagnosis

Primary outcomes

Characterisation of central vestibular syndrome subtypes; Diagnostic differentiation from peripheral vestibular disorders

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