Vestibular migraine (VM) is a prevalent cause of recurrent vertigo with limited standardized treatment options. While vestibular rehabilitation and biofeedback therapy have individually demonstrated efficacy, their combined application and effects on neurobiochemical markers remain unexplored.
Combined biofeedback and vestibular rehabilitation therapy shows clinical benefit for vestibular migraine in this RCT; audiologists and vestibular specialists managing these patients may have evidence to support adding biofeedback to standard rehabilitation protocols, pending full review of effect sizes and methodology.
Vestibular migraine is among the most common causes of episodic vertigo, and identifying effective non-pharmacological combination therapies could meaningfully expand the vestibular rehabilitation toolkit.
- 01RCT design comparing combined biofeedback + vestibular rehabilitation therapy (VRT) for vestibular migraine.
- 02Assessed both clinical outcomes (symptoms, function) and neurobiochemical markers.
- 03Published in Frontiers in Neurology (2026); doi 10.3389/fneur.2026.1861115.
- 04Addresses a gap in evidence for non-drug management of vestibular migraine.
- 05Neurobiochemical correlates may help explain the mechanism behind therapy-related improvement.
Combined biofeedback and vestibular rehabilitation therapy is clinically efficacious for vestibular migraine.
studypartially supportedThe combination therapy produces measurable changes in neurobiochemical correlates in vestibular migraine patients.
studyunclear- PMID
- 42416381
- DOI
- 10.3389/fneur.2026.1861115.
- Journal
- Frontiers in Neurology
- Publication type
- research_article
- Evidence level
- 1b
- Population
- Patients with vestibular migraine
- Intervention
- Combined biofeedback and vestibular rehabilitation therapy
- Comparator
- Unclear — likely VRT alone, biofeedback alone, or standard care
Primary outcomes
Clinical efficacy (symptom and functional outcomes); Neurobiochemical correlates