Motion sickness is a common and often debilitating condition arising from sensory conflict within the vestibular-visual-proprioceptive system, with downstream activation of autonomic and emetic pathways. Despite its prevalence in travel, maritime operations, aviation, spaceflight, and virtual environments, effective prophylaxis remains limited by adverse side effects....
✦ The floor
Discussion
Signed responses from readers of the wire.
Single case report — no actionable change; interesting hypothesis-generating finding for clinicians managing refractory vestibular-related motion sickness, but no evidence base to support adoption.
Stellate ganglion block is an emerging intervention for several sensory and autonomic conditions; this case adds vestibular-driven motion sickness to the list of potential indications warranting prospective study.
- 01Long-standing severe motion sickness resolved following a stellate ganglion block (a neck nerve injection).
- 02The underlying mechanism is proposed as sensory conflict between the vestibular, visual, and proprioceptive systems.
- 03Evidence is limited to a single patient — N=1 case report.
- 04Stellate ganglion block is already used for other conditions but is not an established vestibular treatment.
- 05Prospective controlled trials are needed before any clinical recommendation.
Stellate ganglion block resolved long-standing severe motion sickness caused by vestibular-visual-proprioceptive sensory conflict.
studypartially supported- PMID
- 42182058
- DOI
- 10.3389/fnins.2026.1811989.
- Journal
- Frontiers in Neuroscience
- Publication type
- case_report
- Evidence level
- 4
- Sample size
- 1
- Population
- Single patient with long-standing severe motion sickness
- Intervention
- Stellate ganglion block
Primary outcomes
Resolution or reduction of motion sickness symptoms