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Postural Stability, Fall Risk, and Effects of Balance-Based Exercise in Acromegaly

A dispatch from PubMed — filed

Acromegaly may impair balance and increase fall risk. We aimed to evaluate postural stability, fall risk, and vestibulo-ocular reflex function in patients with acromegaly and to assess the effects of a balance-oriented exercise program.

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Discussion

Signed responses from readers of the wire.

Clinical Takeaway

Audiologists and vestibular specialists working with acromegaly patients should be alert to increased fall risk and compromised vestibulo-ocular reflex function; balance-based exercise may be a useful adjunct referral recommendation.

Why It Matters

Vestibular dysfunction and fall risk in acromegaly represent an under-recognized clinical intersection between endocrinology and audiology/vestibular medicine, broadening the case for interdisciplinary care.

Key Points
  1. 01Acromegaly (excess growth hormone disorder) is associated with impaired postural stability and increased fall risk.
  2. 02Vestibulo-ocular reflex (the eye-movement reflex linked to balance) was evaluated and found to be affected.
  3. 03Balance-based exercise interventions were assessed for their ability to reduce fall risk in this population.
  4. 04Findings highlight an underappreciated vestibular burden in patients with acromegaly.
  5. 05Interdisciplinary care involving vestibular specialists may benefit acromegaly patients.
Claims & Evidence

Patients with acromegaly have impaired postural stability and elevated fall risk.

studysupported

Balance-based exercise interventions ameliorate postural instability in acromegaly patients.

studypartially supported

Vestibulo-ocular reflex function is altered in acromegaly.

studypartially supported
Research metadata
PMID
42592857
DOI
10.1093/ejendo/lvag154.
Journal
European Journal of Endocrinology
Publication type
research_article
Evidence level
2b
Population
Patients diagnosed with acromegaly
Intervention
Balance-based exercise intervention
Comparator
Baseline or non-exercising acromegaly patients (implied)

Primary outcomes

Postural stability measures; Fall risk assessment; Vestibulo-ocular reflex function

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