This study evaluated interpeak latency (IPL) and its intertrial variability (IPLVAR) of the electrically evoked compound action potential (eCAP) as potential alternatives to the phase-locking value (PLV) for quantifying auditory nerve (AN) synchrony in cochlear implant (CI) users.
eCAP N1-P2 interpeak latency and its variability show potential as non-invasive markers of neural synchrony in cochlear implant users, but clinical adoption requires validation in larger, prospective studies with outcome correlations before integration into routine programming.
Reliable objective markers of auditory nerve health in cochlear implant users could enable more personalised device programming and predict speech understanding outcomes.
- 01Study evaluated N1-P2 interpeak latency of eCAP as a marker of auditory nerve neural synchrony in CI users.
- 02Intertrial variability of eCAP was also assessed as a potential indicator of neural function.
- 03Published in the Journal of the Association for Research in Otolaryngology (JARO).
- 04Objective eCAP measures could complement or reduce reliance on behavioural testing in CI programming.
- 05Findings are exploratory; clinical utility depends on further validation against speech perception outcomes.
N1-P2 interpeak latency of the eCAP is a potential indicator of neural synchrony in the auditory nerve of cochlear implant users.
studypartially supportedIntertrial variability of eCAP N1-P2 interpeak latency reflects neural synchrony in cochlear implant users.
studyunclear- PMID
- 42115509
- DOI
- 10.1007/s10162-026-01051-1.
- Journal
- Journal of the Association for Research in Otolaryngology
- Publication type
- research_article
- Evidence level
- 4
- Population
- Cochlear implant users
- Intervention
- eCAP N1-P2 interpeak latency measurement and intertrial variability analysis
Primary outcomes
N1-P2 interpeak latency of the electrically evoked compound action potential (eCAP); Intertrial variability of eCAP N1-P2 interpeak latency as an indicator of neural synchrony