Currently, there are limited large studies exploring cochlear implantation (CI) outcomes in patients with CHARGE syndrome. We aim to evaluate preoperative and postoperative speech and auditory outcomes in patients with CHARGE syndrome undergoing CI from a review of published single-center studies. DATABASES REVIEWED: PubMed, Scopus, and CINAHL.
Cochlear implantation can yield meaningful speech perception benefits in CHARGE syndrome patients, but outcomes are more variable than in typical candidates; this meta-analysis supports implantation as a viable option while highlighting the need for individualized counseling.
CHARGE syndrome presents unique surgical and rehabilitative challenges, and this first meta-analysis on the topic provides the strongest aggregate evidence yet to guide cochlear implant candidacy decisions in this complex population.
- 01Systematic review and meta-analysis of cochlear implant outcomes specifically in CHARGE syndrome patients.