Supersaccades and Vestibulo-Ocular Reflex Inconsistency Score as Predictors of Gain Recovery After Acute Unilateral Vestibular Loss

OBJECTIVES: To evaluate the predictive value of two novel video head impulse test-derived biomarkers-supersaccades (single covert saccades) and the VOR Inconsistency Score (VIS)-in forecasting early vestibulo-ocular reflex (VOR) gain recovery in patients with unilateral peripheral vestibular dysfunction (UPVD).

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✦ The floor

Discussion

Signed responses from readers of the wire.

✦ Clinical Takeaway ✦

Supersaccades and the VOR Inconsistency Score from vHIT may serve as prognostic biomarkers for VOR gain recovery after acute unilateral vestibular loss, but clinical adoption should await replication in larger, prospective cohorts.

✦ Why It Matters ✦

Identifying reliable early predictors of vestibular recovery could allow clinicians to stratify patients and personalise rehabilitation programmes sooner after acute unilateral vestibular loss.

✦ Key Points ✦

01Study evaluated two vHIT-derived biomarkers: supersaccades and VOR Inconsistency Score.
02Both measures were assessed as predictors of VOR gain recovery after acute unilateral vestibular loss.
03Published in Ear & Hearing, a peer-reviewed audiology/vestibular journal.
04Findings may support earlier, targeted vestibular rehabilitation decision-making.
05Prognostic accuracy and clinical thresholds need validation in larger populations.

✦ Claims & Evidence ✦

ClaimEvidenceSupport

Supersaccades derived from vHIT predict VOR gain recovery after acute unilateral vestibular loss.

studypartially supported

VOR Inconsistency Score derived from vHIT predicts VOR gain recovery after acute unilateral vestibular loss.

studypartially supported

✦ Research metadata ✦

PMID: 42610586
DOI: 10.1097/AUD.0000000000001841.
Journal: Ear and Hearing
Publication type: research_article
Evidence level: 2b
Population: Patients with acute unilateral vestibular loss
Intervention: Video head impulse test (vHIT)-derived biomarkers: supersaccades and VOR Inconsistency Score

Primary outcomes

VOR gain recovery after acute unilateral vestibular loss

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