✦ Clinical Takeaway ✦
Clinicians evaluating patients with Hennebert's sign should include intralabyrinthine schwannoma in the differential diagnosis, even though it is a rare cause.
✦ Why It Matters ✦
Expanding the known differential diagnoses for Hennebert's sign helps prevent misdiagnosis and delays in treating inner-ear tumors.
✦ Key Points ✦
- 01Hennebert's sign (pressure-induced nystagmus) is typically linked to syphilis or perilymph fistula, not inner-ear tumors.
- 02This case report links Hennebert's sign to intralabyrinthine schwannoma for the first time (or rarely).
- 03Single case; no generalisable prevalence data available.
- 04Published in European Archives of Otorhinolaryngology.
- 05Highlights importance of imaging in unexplained vestibular signs.
✦ Claims & Evidence ✦
ClaimEvidenceSupport
Intralabyrinthine schwannoma can present with Hennebert's sign.
studypartially supported✦ Research metadata ✦
- PMID
- 42086991
- DOI
- 10.1007/s00405-026-10238-4.
- Journal
- European Archives of Otorhinolaryngology
- Publication type
- case_report
- Evidence level
- 4
- Population
- Single patient presenting with Hennebert's sign
- Intervention
- Diagnostic evaluation for intralabyrinthine schwannoma
Primary outcomes
Identification of intralabyrinthine schwannoma as cause of Hennebert's sign