Paget disease of bone (PDB) is a focal skeletal disorder characterized by excessive and disorganized bone remodeling. When the skull is involved, the disease may also affect the temporal bones. We present the case of a 68-year-old woman referred for evaluation of persistently elevated alkaline phosphatase (ALP), ultimately diagnosed with Paget disease of the calvarium with bilateral temporal bone involvement....
✦ The floor
Discussion
Signed responses from readers of the wire.
Audiologists should be aware that Paget disease involving the temporal bone can cause progressive mixed or sensorineural hearing loss and vestibular symptoms; however, this single case report does not change established screening or management protocols.
Paget disease is a rare but underrecognized cause of progressive hearing loss in older adults, and awareness among audiologists can prompt timely referral for medical workup when unexplained or atypical audiometric patterns are encountered.
- 01Paget disease of the calvarium (skull) can involve the temporal bone, impacting auditory and vestibular function.
- 02Hearing loss from Paget disease may be sensorineural, conductive, or mixed depending on the structures affected.
- 03Case reports provide limited evidence but raise awareness of rare differential diagnoses.
- 04Early recognition and referral to an otolaryngologist or metabolic bone specialist is key for management.
- 05Published in Cureus as a single case report, limiting generalizability.
Paget disease of the calvarium can affect the temporal bone and cause auditory and vestibular dysfunction.
studysupported- PMID
- 42928824
- DOI
- 10.7759/cureus.116917.
- Journal
- Cureus
- Publication type
- case_report
- Evidence level
- 4
- Sample size
- 1
- Population
- Single patient with Paget disease of the calvarium involving the temporal bone
- Intervention
- Clinical description and workup of Paget disease with temporal bone involvement
Primary outcomes
Description of auditory and vestibular manifestations of calvarial Paget disease