Cogan's syndrome (CS) is a rare autoimmune disorder involving audio-vestibular and ocular inflammation. While systemic vasculitis is a known complication, its association with Moyamoya-type cerebrovascular remodeling has not been previously documented....
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Discussion
Signed responses from readers of the wire.
No actionable change — this is a single case report of a rare co-occurrence; findings are hypothesis-generating only and do not support changes to diagnostic or treatment protocols.
Documenting rare overlaps between vascular and autoimmune disorders can help clinicians consider broader systemic workups when patients present with combined audio-vestibular and cerebrovascular findings.
- 01Case report documents rare co-occurrence of Moyamoya vasculopathy and atypical Cogan's syndrome.
- 02Cogan's syndrome involves autoimmune inflammation of the inner ear and eyes, causing hearing and balance problems.
- 03Moyamoya disease involves progressive narrowing of brain arteries, leading to stroke risk.
- 04The overlap may point to a shared immune-mediated or vascular pathophysiology.
- 05Published in Archives of Clinical Medicine Case Reports, 2026.
Moyamoya vasculopathy and atypical Cogan's syndrome can co-occur in the same patient.
studypartially supported- PMID
- 42569329
- DOI
- 10.26502/acmcr.96550761.
- Journal
- Archives of Clinical Medicine Case Reports
- Publication type
- case_report
- Evidence level
- 4
- Sample size
- 1
- Population
- Single patient with co-occurring Moyamoya vasculopathy and atypical Cogan's syndrome
- Intervention
- Clinical description of Moyamoya vasculopathy with atypical Cogan's syndrome
Primary outcomes
Clinical characterization of co-occurring Moyamoya vasculopathy and atypical Cogan's syndrome