Vestibular schwannoma (VS) stereotactic radiosurgery (SRS) requires high target conformality and rapid dose falloff to spare adjacent organs at risk (OARs), particularly the brainstem. HyperArc (HA) is an automated noncoplanar volumetric-modulated arc therapy (VMAT) approach designed to standardize and streamline cranial SRS planning and delivery....
No actionable change for most audiologists — dosimetric comparison findings are relevant to radiation oncology and neurosurgery planning teams managing vestibular schwannoma; audiologists involved in pre/post-radiosurgery hearing monitoring should note that both technologies aim to spare cochlear and neural structures, but this study does not report hearing outcome data.
Vestibular schwannoma is a key diagnosis managed across audiology, neurotology, and oncology; optimizing radiosurgery planning to spare hearing-critical structures directly affects the audiological outcomes of treated patients.
- 01Dosimetric (radiation dose distribution) comparison of HyperArc vs. CyberKnife for vestibular schwannoma radiosurgery.
- 02Both systems were evaluated on target conformality and sparing of organs at risk (brainstem, cochlea, etc.).
- 03Single-fraction stereotactic radiosurgery was the treatment modality studied.
- 04Study did not report clinical hearing or tumor-control outcomes — purely dosimetric.
- 05Results may inform radiation oncology team decisions but do not directly change audiology practice.
HyperArc and CyberKnife differ in target conformality and organ-at-risk sparing for vestibular schwannoma single-fraction radiosurgery.
studypartially supported- PMID
- 42073535
- DOI
- 10.3390/cancers18081207.
- Journal
- Cancers
- Publication type
- research_article
- Evidence level
- 4
- Population
- Patients with vestibular schwannoma treated with single-fraction stereotactic radiosurgery
- Intervention
- Automated noncoplanar VMAT (HyperArc)
- Comparator
- CyberKnife stereotactic radiosurgery
Primary outcomes
Target conformality; Organ-at-risk dose sparing (brainstem, cochlea, optic structures)