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Persistent postural-perceptual dizziness: subjective-objective dissociation and response to neurologist-led multimodal therapy

A dispatch from PubMed — filed

AND OBJECTIVES: Persistent postural-perceptual dizziness (PPPD) is characterized by maladaptive central sensory processing and frequent psychiatric comorbidity. Prospective outcome data, particularly from low- and middle-income settings, remain limited....

Clinical Takeaway

Neurologist-led multimodal therapy shows promise for PPPD, but until full results and sample details are reviewed, audiologists should note this as supportive context for multidisciplinary referral pathways rather than a prompt to change current vestibular rehabilitation protocols.

Why It Matters

PPPD is one of the most common chronic vestibular disorders and remains underserved by single-discipline approaches; this study reinforces the case for coordinated, multimodal care models.

Key Points
  1. 01PPPD is characterized by chronic dizziness that persists despite normal objective vestibular test results.
  2. 02Subjective-objective dissociation is a defining feature and a key diagnostic challenge in PPPD.
  3. 03A neurologist-led multimodal therapy protocol was evaluated prospectively for outcomes in PPPD.
  4. 04Published in Journal of Neurology (2026), adding to the growing evidence base for PPPD management.
  5. 05Findings may support interdisciplinary referral between audiology, neurology, and vestibular therapy teams.
Claims & Evidence

PPPD involves a dissociation between patients' subjective dizziness experience and objective vestibular test findings.

studysupported

Neurologist-led multimodal therapy produces measurable improvements in PPPD outcomes.

studypartially supported
Research metadata
PMID
42268441
DOI
10.1007/s00415-026-13927-6.
Journal
Journal of Neurology
Publication type
research_article
Evidence level
2b
Population
Patients with persistent postural-perceptual dizziness (PPPD)
Intervention
Neurologist-led multimodal therapy for PPPD

Primary outcomes

Subjective dizziness severity; Objective vestibular test outcomes; Treatment response to multimodal therapy

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