Sensorineural hearing loss (SNHL) accompanied by vertigo is a condition with clinical heterogeneity. Understanding vascular underpinnings is crucial for management. OBJECTIVE: To investigate the association of systemic hemodynamics and endothelial dysfunction with the distinct clinical manifestations of SNHL with vertigo.
Cross-sectional associations between hemodynamic markers and hearing-loss-plus-vertigo phenotypes are hypothesis-generating only; no actionable diagnostic or treatment change is supported by this design.
Identifying vascular contributors to sensorineural hearing loss with vertigo could eventually inform targeted therapies, but this cross-sectional study is an early step requiring longitudinal validation.
- 01Cross-sectional analysis published in Journal of Otolaryngology – Head & Neck Surgery.
- 02Investigates links between systemic blood pressure/flow and endothelial (blood vessel lining) dysfunction in patients with sensorineural hearing loss and vertigo.
- 03Aims to distinguish clinical subtypes (phenotypes) of this combined condition.
- 04Cross-sectional design cannot establish causality between vascular factors and hearing/balance symptoms.
- 05Published DOI: 10.1177/19160216261454997.
Systemic hemodynamic abnormalities and endothelial dysfunction are associated with distinct clinical phenotypes in sensorineural hearing loss with vertigo.
studypartially supported- PMID
- 42439328
- DOI
- 10.1177/19160216261454997.
- Journal
- Journal of Otolaryngology – Head & Neck Surgery
- Publication type
- research_article
- Evidence level
- 3
- Population
- Patients with sensorineural hearing loss accompanied by vertigo
- Intervention
- Assessment of systemic hemodynamics and endothelial dysfunction
Primary outcomes
Association between hemodynamic/endothelial markers and clinical phenotypes of sensorineural hearing loss with vertigo