Journal article · Vestibular← The news desk

✦ The Dispatch

Association between serum 25-hydroxyvitamin D levels and prognosis in benign paroxysmal positional vertigo

A dispatch from PubMed — filed

Benign paroxysmal positional vertigo (BPPV) is a common peripheral vestibular disorder in which early nonresponse and recurrence remain clinically important. Vitamin D has been hypothesized to influence otoconial stability and inner-ear mineral homeostasis and may be associated with BPPV prognosis....

Clinical Takeaway

Low vitamin D may be associated with worse BPPV prognosis and higher recurrence; audiologists and ENT clinicians managing BPPV patients could consider flagging low vitamin D for physician follow-up, though this study alone is insufficient to change standard repositioning treatment protocols.

Why It Matters

If confirmed in prospective trials, vitamin D supplementation could become a simple, low-cost adjunct to reduce BPPV recurrence — a meaningful quality-of-life improvement for a very common vestibular condition.

Key Points
  1. 01Study published in Frontiers in Nutrition examined serum 25-hydroxyvitamin D levels in BPPV patients.
  2. 02Lower vitamin D levels were associated with poorer treatment outcomes and higher recurrence rates.
  3. 03BPPV is the most common cause of positional vertigo, making this finding broadly clinically relevant.
  4. 04Observational/prognostic design; causality and optimal supplementation thresholds not yet established.
  5. 05Supports growing body of literature linking vitamin D deficiency to vestibular dysfunction.
Claims & Evidence

Lower serum 25-hydroxyvitamin D levels are associated with worse prognosis and higher recurrence rates in BPPV.

studypartially supported
Research metadata
PMID
42325514
DOI
10.3389/fnut.2026.1805821.
Journal
Frontiers in Nutrition
Publication type
research_article
Evidence level
2b
Population
Patients diagnosed with benign paroxysmal positional vertigo (BPPV)
Intervention
Measurement of serum 25-hydroxyvitamin D levels

Primary outcomes

Treatment outcome (success/failure of canalith repositioning); BPPV recurrence rate

Related stories