132 - Ross O'Neill, PhD & Hubert Lim, PhD - Lenire: The First FDA-Approved Bimodal Tinnitus Treatment

Guests: Ross O'Neill Ph.D (Founding CEO) & Hubert Lim Ph.D (Chief Scientific Officer) of Neuromod Dave is joined by Ross & Hubert to discuss: - The backstory of how Ross & Hubert met and ultimately partnered together on Lenire - Hubert's research and papers he wrote about paired stimulation & Pavlovian conditioning, which included data that identified tongue stimulation combined with sound as a promising direction...

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This double-blind RCT on Musical Auditory Training for tinnitus is the strongest design available for this question; if results are positive, audiologists should consider MAT as an evidence-based adjunct to tinnitus management — await full results and effect-size data before...

PubMed·Journal article·Tinnitus·3w ago

Otolithic Dysfunction in Normal-Hearing Individuals With Tinnitus

Consider adding otolith function testing (e.g., cVEMP/oVEMP) to the assessment battery for normal-hearing tinnitus patients, as subclinical cochleovestibular dysfunction may be present before measurable hearing loss develops.

PubMed·Journal article·Tinnitus·6w ago

Can Tinnitus Cause Speech-in-Noise Deficits?

alone; await full-text review before changing how you counsel tinnitus patients about speech-in-noise difficulties.

PubMed·Journal article·Tinnitus·5h ago

Development and Validation of a Nomogram to Identify and Predict High-Distress Psychosocial Phenotypes in Tinnitus Patients: A Latent Profile Analysis

Audiologists and tinnitus clinicians should note this validated nomogram as a potential early-screening tool for high-distress psychosocial risk in tinnitus patients, though external validation in broader populations is needed before routine clinical adoption.

PubMed·Clinical trial·Tinnitus·8w ago

Mobile Application as a Digital Therapeutic for Chronic Tinnitus: A Randomized Clinical Trial

If the app demonstrated significant efficacy, audiologists managing chronic tinnitus patients should consider whether a CBT-based digital therapeutic could complement or extend clinic-based tinnitus management — specific outcome data from the trial should be reviewed before...

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Clinicians should consider applying the proposed tinnitus vs. tinnitus disorder distinction in intake assessments, as it may better identify patients who need psychological or autonomic co-management beyond standard audiological care.

PubMed·Journal article·Tinnitus·7w ago

EEG Spectral Analysis of Tinnitus Sound Therapy: Meta-Analysis

This meta-analysis provides neurophysiological evidence supporting sound therapy's effect on brain activity in chronic tinnitus, but clinicians should interpret EEG outcomes cautiously as surrogate markers until they are linked to validated patient-reported symptom improvement.

PubMed·Journal article·Tinnitus·5d ago

Temporal bone remodeling after venous stenting for pulsatile tinnitus: isolated dehiscence versus diverticulum

Clinicians managing pulsatile tinnitus with venous sinus stenting should be aware that the type of structural abnormality — isolated dehiscence versus diverticulum — is associated with different rates of post-stenting temporal bone remodeling, which may inform procedural...