OBJECTIVES: Vestibular and oculomotor abnormalities have been widely identified in Fabry disease (FD), with inflammation potentially playing an important role. We aim to investigate the expression of inflammatory cytokines (ICs) in FD patients and their relationship with the vestibular/oculomotor dysfunctions.
Audiologists and vestibular specialists managing Fabry disease patients should be aware that inflammatory cytokine levels may correlate with vestibular and oculomotor dysfunction, though this does not yet change vestibular assessment or treatment protocols.
Identifying inflammation as a driver of vestibular and oculomotor dysfunction in Fabry disease opens potential avenues for monitoring disease progression and targeting anti-inflammatory therapies.
- 01Prospective longitudinal study links multiple inflammatory cytokines to vestibular and oculomotor dysfunction in Fabry disease.