Ménière's disease (MD) is a chronic inner ear syndrome characterized by vertigo, tinnitus, and fluctuating sensorineural hearing loss. Despite its well-defined clinical presentation, the underlying pathophysiology remains elusive, often resulting in empirical and partially effective treatments....
✦ Clinical Takeaway ✦
Preliminary metabolomics findings suggest Ménière's disease has systemic metabolic involvement, but this is exploratory science — no actionable change for clinical practice at this stage.
✦ Why It Matters ✦
Identifying systemic metabolic signatures in Ménière's disease could open pathways for biomarker-based diagnosis and novel therapeutic targets beyond endolymphatic hydrops management.
✦ Key Points ✦
- 01Urinary 1H NMR metabolomics reveals systemic metabolic alterations specific to Ménière's disease.
- 02