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A familial case series of refractory head noise, tinnitus, and sleep disorders caused by internal jugular vein stenosis: illustrative cases

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The authors report a rare familial case series of 3 patients with internal jugular vein stenosis (IJVS). These patients presented primarily with head noise, tinnitus, or sleep disorders, respectively. OBSERVATIONS: After other possible causes were excluded, novel surgical interventions were performed....

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Discussion

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Clinical Takeaway

Clinicians evaluating refractory pulsatile tinnitus should consider internal jugular vein stenosis as a cause, including in family members of affected patients; however, this 3-case series is too preliminary to change screening protocols.

Why It Matters

Familial internal jugular vein stenosis as a cause of refractory tinnitus is virtually unreported, raising the possibility of a heritable vascular contribution to pulsatile tinnitus that warrants further investigation.

Key Points
  1. 01Three relatives presented with refractory head noise, tinnitus, and sleep disturbance linked to internal jugular vein stenosis.
  2. 02Familial clustering of IJV stenosis causing tinnitus is extremely rare and has not been well-characterized in the literature.
  3. 03The cases suggest a potential hereditary vascular etiology for a subset of refractory pulsatile tinnitus.
  4. 04Published as illustrative case lessons—exploratory, hypothesis-generating evidence only.
Claims & Evidence

Internal jugular vein stenosis can present as a familial condition causing refractory head noise, tinnitus, and sleep disorders.

studypartially supported
Research metadata
PMID
42766864
DOI
10.3171/CASE25693.
Journal
Journal of Neurosurgery: Case Lessons
Publication type
case_report
Evidence level
4
Sample size
3
Population
Three family members presenting with refractory head noise, tinnitus, and sleep disorders attributed to internal jugular vein stenosis
Intervention
Diagnosis and characterization of internal jugular vein stenosis

Primary outcomes

Clinical presentation of refractory tinnitus and head noise; Familial pattern of internal jugular vein stenosis; Association with sleep disorders

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