(S): Endolymphatic hydrops is associated with factors such as autoimmune responses and vascular issues. Vitamin D plays a vital role in immune regulation and is associated with various inflammatory conditions. However, evidence regarding the correlation between endolymphatic hydrops and vitamin D is lacking....
If the study confirms a significant association, clinicians managing Ménière's disease or endolymphatic hydrops may consider routine vitamin D screening; however, evidence is not yet sufficient to recommend this as standard practice.
Identifying a modifiable factor like vitamin D deficiency as associated with endolymphatic hydrops could open a low-cost intervention pathway for a condition with limited treatment options.
- 01Study links endolymphatic hydrops (inner ear fluid build-up) with MRI findings and serum vitamin D levels.
- 02MRI is increasingly used to directly visualize endolymphatic hydrops in vivo.
- 03Vitamin D deficiency may be a modifiable risk factor for inner ear fluid disorders.
- 04Published in the Brazilian Journal of Otorhinolaryngology (2026).
- 05Findings are observational; causality between low vitamin D and hydrops has not been established.
Endolymphatic hydrops is associated with lower serum vitamin D levels.
studyunclearMRI findings correlate with the presence and severity of endolymphatic hydrops.
studypartially supported- PMID
- 42302466
- DOI
- 10.1016/j.bjorl.2026.101858.
- Journal
- Brazilian Journal of Otorhinolaryngology
- Publication type
- research_article
- Evidence level
- 3
- Population
- Patients diagnosed with endolymphatic hydrops undergoing MRI evaluation
- Intervention
- Assessment of serum vitamin D levels and MRI imaging of the inner ear
- Comparator
- Patients without endolymphatic hydrops or varying vitamin D levels
Primary outcomes
Association between serum vitamin D levels and endolymphatic hydrops; Correlation of MRI findings with hydrops diagnosis