: Vascular mechanisms have been implicated in idiopathic acute unilateral audiovestibulopathy (iAUAV, also known as labyrinthitis), especially in older patients. We investigated the platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and white matter changes in patients with iAUAV/labyrinthitis to determine the potential vascular etiology in this disorder....
Consider vascular risk factors and inflammatory blood markers (NLR, PLR) when evaluating older patients with sudden unexplained hearing and balance loss, but await larger confirmatory studies before changing diagnostic protocols.
If vascular mechanisms are confirmed in a subset of labyrinthitis cases, it could shift management toward cardiovascular risk reduction rather than purely anti-inflammatory or antiviral treatment.
- 01Study investigates blood vessel–related causes of sudden, unexplained hearing and balance loss (idiopathic labyrinthitis).