The spatiotemporal structure of muscle coordination emerges from the collaboration and competition among cortical, brainstem and spinal pathways onto motor neuron pools, each continuously shaped by task demands, limb position and descending tract integrity....
No actionable change for audiology practice; these findings are primarily relevant to neurology and vestibular rehabilitation research rather than routine audiological care.
Demonstrating ipsilesional brainstem pathway disruption via galvanic vestibular stimulation advances understanding of the vestibulo-motor deficits underlying post-stroke balance impairment, potentially guiding future rehabilitation targets.
- 01Galvanic vestibular stimulation (GVS) was applied to hemiparetic stroke survivors to probe balance pathways.
- 02Ipsilesional (same side as stroke) brainstem vestibular pathways were found to be disrupted.
- 03Cortical, brainstem, and spinal contributions to muscle coordination were examined.
- 04Findings help explain the complex balance deficits seen after stroke beyond simple limb weakness.
- 05GVS is used here as a non-invasive research tool rather than a treatment.
Galvanic vestibular stimulation reveals disruption of ipsilesional brainstem pathways in hemiparetic stroke survivors.
studysupportedBalance and muscle coordination deficits in hemiparetic stroke reflect cortical, brainstem, and spinal vestibular pathway involvement.
studypartially supported- PMID
- 42173690
- DOI
- 10.1113/EP093389.
- Journal
- Experimental Physiology
- Publication type
- research_article
- Evidence level
- 4
- Population
- Hemiparetic stroke survivors
- Intervention
- Galvanic vestibular stimulation (GVS) to probe brainstem and spinal vestibular pathways
Primary outcomes
Ipsilesional brainstem pathway integrity; Cortical, brainstem, and spinal contributions to muscle coordination responses