Clinical experience with the diagnosis and treatment of middle ear adenomatous neuroendocrine tumors

Middle ear adenoma, also known as middle ear adenomatous neuroendocrine tumors (MEANTs), is a rare neoplasm, accounting for < 2% of all middle ear tumors. It is characterized by slow growth, non-invasive behavior, and nonspecific symptoms, which often complicate preoperative diagnosis. This review summarizes our clinical experience in the diagnosis and treatment of 11 cases of MEANT....

For clinicians who encounter suspected middle ear adenomatous neuroendocrine tumors, this retrospective series offers practical diagnostic and surgical management insights, but the rare nature and small case numbers mean evidence is limited — individualized multidisciplinary assessment remains essential.

Rare middle ear neoplasms are frequently misdiagnosed; this clinical series adds to the limited literature guiding audiologists and otologists on recognition, workup, and referral pathways for these tumors.

1. 01Retrospective review of diagnosis and treatment of middle ear adenomatous neuroendocrine tumors.
2. 02These tumors represent fewer than 2% of all middle ear tumors, making them extremely rare.
3. 03Published in the American Journal of Translational Research (AJTR).
4. 04Study provides clinical experience data to guide recognition and management decisions.
5. 05Retrospective design and rarity of condition limit the strength of conclusions.

PMID

42491072

DOI

10.62347/AJYW4462.

Journal

American Journal of Translational Research

Publication type

research_article

Evidence level

4

Population

Patients with middle ear adenomatous neuroendocrine tumors

Intervention

Diagnosis and treatment approaches for middle ear adenomatous neuroendocrine tumors