We sought to analyze contemporary clinical trials since 2010 involving vestibular schwannoma (VS) patients undergoing microsurgical resection to characterize the landscape of trial outcomes studied, as well as the representation of recruited participants by sex, race, and ethnicity. DATABASES REVIEWED: PubMed, Embase, CENTRAL, and Web of Science.
This scoping review maps the clinical trial landscape for vestibular schwannoma surgery but does not yet provide new outcome data; clinicians should watch for future systematic reviews or pooled analyses that may follow from this groundwork.
Identifying gaps and inconsistencies in vestibular schwannoma surgical trial design can guide more standardized, higher-quality future research that could eventually change surgical practice.
- 01Scoping review covers clinical trials on vestibular schwannoma microsurgery published since 2010.
- 02Published in Otology & Neurotology (PMID 42083075, DOI 10.1097/MAO.0000000000004932).
- 03Characterizes the research landscape rather than synthesizing efficacy outcomes.
- 04Likely highlights heterogeneity in outcome measures and trial designs.
- 05Identifies where standardization and further clinical trials are needed.
The scoping review characterizes the landscape of clinical trials on microsurgical resection of vestibular schwannoma since 2010.
studysupported- PMID
- 42083075
- DOI
- 10.1097/MAO.0000000000004932.
- Journal
- Otology & Neurotology
- Publication type
- review
- Evidence level
- 2a
- Population
- Clinical trials involving patients undergoing microsurgical resection of vestibular schwannoma
- Intervention
- Microsurgical resection of vestibular schwannoma
Primary outcomes
Characterization of clinical trial landscape since 2010; Identification of research gaps and outcome measure heterogeneity