OBJECTIVES: This study quantitatively assessed the neurophysiological differences in mismatch negativity (MMN) responses between cochlear implant (CI) users and normal hearing (NH) listeners. Through meta-analysis, we examined effect size differences and statistical significance in MMN latency and amplitude between these groups....
✦ The floor
Discussion
Signed responses from readers of the wire.
MMN differences between cochlear implant users and normal-hearing listeners are quantified across age groups, but these neurophysiological findings are not yet mature enough to change routine clinical fitting or programming protocols.
Quantifying age-related MMN divergences in cochlear implant users versus normal-hearing controls may help set realistic expectations for auditory cortex (brain hearing center) maturation and guide rehabilitation timelines.
- 01Multilevel meta-analysis synthesizes MMN (automatic brain sound-detection response) data across multiple studies.
- 02Compares cochlear implant users with normal-hearing listeners across different age groups.
- 03MMN latency (timing) and amplitude (size) are both analyzed.
- 04Age-dependent cortical (brain) dynamics are a key focus.
- 05Published in Ear and Hearing (DOI: 10.1097/AUD.0000000000001857).
Cochlear implant users show significantly different MMN latency and amplitude compared to normal-hearing listeners.
studysupportedMMN divergences between cochlear implant users and normal-hearing listeners vary as a function of age.
studypartially supported- PMID
- 42507811
- DOI
- 10.1097/AUD.0000000000001857.
- Journal
- Ear and Hearing
- Publication type
- meta_analysis
- Evidence level
- 1a
- Population
- Cochlear implant users and normal-hearing listeners across pediatric and adult age groups
- Intervention
- Cochlear implantation (auditory stimulation via cochlear implant)
- Comparator
- Normal-hearing listeners
Primary outcomes
Mismatch negativity (MMN) latency; Mismatch negativity (MMN) amplitude