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Relative Brain Perfusion Differences in a Patient With Persistent Neurocognitive and Vestibular Symptoms Associated With Post-COVID-19 Condition: A Case Report

A dispatch from PubMed — filed

Post-COVID-19 condition may present with persistent subjective cognitive and vestibular symptoms despite unrevealing conventional diagnostic evaluation. We report the case of a 67-year-old woman who developed persistent subjective cognitive symptoms ("brain fog"), dizziness, vertigo, and imbalance following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection....

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✦ The floor

Discussion

Signed responses from readers of the wire.

Clinical Takeaway

No actionable change — a single-patient case report cannot support clinical decision-making; it illustrates that post-COVID vestibular symptoms may correlate with detectable brain perfusion changes but provides no guidance for audiological management.

Why It Matters

This case highlights that post-COVID-19 vestibular and cognitive symptoms may have an identifiable neurological basis (altered brain blood flow), which is relevant for audiologists and vestibular specialists managing long-COVID patients.

Key Points
  1. 01Single case report of a 67-year-old with persistent cognitive and vestibular symptoms following COVID-19 infection.
  2. 02Brain perfusion imaging revealed regional blood-flow differences potentially linked to the patient's symptoms.
  3. 03Published in Cureus, an open-access journal; evidence level is very low (case report).
  4. 04Vestibular symptoms are a recognised but poorly understood feature of long-COVID.
  5. 05Findings are hypothesis-generating only and cannot be generalised.
Claims & Evidence

Persistent neurocognitive and vestibular symptoms in a post-COVID-19 patient are associated with relative brain perfusion differences on imaging.

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Research metadata
PMID
42729430
DOI
10.7759/cureus.114380.
Journal
Cureus
Publication type
case_report
Evidence level
4
Sample size
1
Population
Single 67-year-old patient with persistent neurocognitive and vestibular symptoms following Post-COVID-19 condition
Intervention
Brain perfusion imaging in post-COVID-19 patient

Primary outcomes

Regional brain perfusion differences on imaging; Association with neurocognitive and vestibular symptom burden

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