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Labyrinthine hemorrhage: practical lessons from a rare cause of acute vestibular syndrome

A dispatch from PubMed — filed

Labyrinthine hemorrhage (LH) is a rare cause of sudden sensorineural hearing loss (SNHL) and acute vestibular syndrome (AVS), which may mimic both peripheral and central etiologies. We report a case of a 76-year-old male on edoxaban therapy presenting with sudden right-sided SNHL and vertigo....

Clinical Takeaway

Clinicians evaluating acute vestibular syndrome (sudden dizziness with balance disruption) should keep labyrinthine hemorrhage in the differential, especially when simultaneous sudden sensorineural hearing loss is present, as MRI with FLAIR/T1 sequences is needed for diagnosis; no practice-changing evidence is introduced, but diagnostic vigilance is reinforced.

Why It Matters

Labyrinthine hemorrhage is easily confused with stroke or Menière's disease, and missed diagnosis can lead to delayed treatment and permanent hearing loss.

Key Points
  1. 01Labyrinthine hemorrhage is a rare but important cause of acute vestibular syndrome and sudden SNHL.
  2. 02Its presentation can mimic both peripheral (inner-ear) and central (brain) vestibular disorders, complicating diagnosis.
  3. 03Case-based format offers practical clinical lessons for recognition and differential diagnosis.
  4. 04MRI is critical for distinguishing labyrinthine hemorrhage from stroke and other etiologies.
  5. 05Early identification may limit permanent auditory and vestibular damage.
Claims & Evidence

Labyrinthine hemorrhage can mimic both peripheral and central causes of acute vestibular syndrome.

studypartially supported

Labyrinthine hemorrhage is a rare cause of acute vestibular syndrome and sudden sensorineural hearing loss.

studysupported
Research metadata
PMID
42119528
DOI
10.1055/s-0046-1818604.
Journal
Seminars in Hearing
Publication type
case_report
Evidence level
4
Population
Patients presenting with acute vestibular syndrome and sudden sensorineural hearing loss attributed to labyrinthine hemorrhage
Intervention
Clinical review and case-based analysis of labyrinthine hemorrhage presentation and diagnosis

Primary outcomes

Clinical characterization of labyrinthine hemorrhage presentation; Differentiation from peripheral and central vestibular etiologies

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