OBJECTIVES: NF2-related schwannomatosis (NF2) is an autosomal dominant syndrome resulting in a predisposition for benign tumors of the nervous system, including schwannomas, meningiomas, and ependymomas. There is a lack of data on the prevalence of trigeminal neuralgia (TN) in NF2 and the relationship between trigeminal schwannomas (TS) and TN in NF2 is also unclear....
No actionable change for routine audiology practice; audiologists managing NF2 patients should be aware of trigeminal neuralgia as a possible comorbidity and refer appropriately to neurology or neurosurgery.
NF2-related schwannomatosis frequently presents to audiologists due to vestibular schwannomas (acoustic neuromas), and recognizing associated neurological complications like trigeminal neuralgia supports comprehensive multidisciplinary care.
- 01Trigeminal neuralgia (severe facial nerve pain) can occur in patients with NF2-related schwannomatosis.
- 02NF2-related schwannomatosis is a rare genetic disorder causing multiple benign nerve tumors.
- 03Case-level evidence describes the clinical presentation and management of this combination.
- 04Audiologists seeing NF2 patients should be aware of potential cranial nerve pain complications.
- 05Findings reinforce the need for multidisciplinary management of NF2-related schwannomatosis.
Trigeminal neuralgia can present as a complication in patients with NF2-related schwannomatosis.
studypartially supported- PMID
- 42095036
- DOI
- 10.1055/a-2607-6174.
- Journal
- Laryngoscope
- Publication type
- case_report
- Evidence level
- 4
- Population
- Patients with NF2-related schwannomatosis presenting with trigeminal neuralgia
- Intervention
- Clinical characterisation of trigeminal neuralgia in NF2-related schwannomatosis
Primary outcomes
Clinical presentation of trigeminal neuralgia in NF2 patients; Management outcomes