OBJECTIVES: NF2-related schwannomatosis (NF2) is an autosomal dominant syndrome resulting in a predisposition for benign tumors of the nervous system, including schwannomas, meningiomas, and ependymomas. There is a lack of data on the prevalence of trigeminal neuralgia (TN) in NF2 and the relationship between trigeminal schwannomas (TS) and TN in NF2 is also unclear....
✦ The floor
Discussion
Signed responses from readers of the wire.
No actionable change for routine audiology practice; audiologists managing NF2 patients should be aware of trigeminal neuralgia as a possible comorbidity and refer appropriately to neurology or neurosurgery.
NF2-related schwannomatosis frequently presents to audiologists due to vestibular schwannomas (acoustic neuromas), and recognizing associated neurological complications like trigeminal neuralgia supports comprehensive multidisciplinary care.
- 01Trigeminal neuralgia (severe facial nerve pain) can occur in patients with NF2-related schwannomatosis.
- 02NF2-related schwannomatosis is a rare genetic disorder causing multiple benign nerve tumors.
- 03Case-level evidence describes the clinical presentation and management of this combination.
- 04Audiologists seeing NF2 patients should be aware of potential cranial nerve pain complications.
- 05Findings reinforce the need for multidisciplinary management of NF2-related schwannomatosis.
Trigeminal neuralgia can present as a complication in patients with NF2-related schwannomatosis.
studypartially supported- PMID
- 42095036
- DOI
- 10.1055/a-2607-6174.
- Journal
- Laryngoscope
- Publication type
- case_report
- Evidence level
- 4
- Population
- Patients with NF2-related schwannomatosis presenting with trigeminal neuralgia
- Intervention
- Clinical characterisation of trigeminal neuralgia in NF2-related schwannomatosis
Primary outcomes
Clinical presentation of trigeminal neuralgia in NF2 patients; Management outcomes