Multimodal Audiovestibular Assessment After Intratympanic Gentamicin for Vestibular Drop Attacks in Meniere's Disease: A Case Report and Focused Review

and Clinical Significance: Vestibular drop attacks are a rare but disabling manifestation of Ménière's disease. This study aimed to demonstrate the value of multimodal audiovestibular assessment in documenting vestibular deficit after intratympanic gentamicin therapy....

Multimodal audiovestibular assessment (combining multiple hearing and balance tests) appears useful for monitoring treatment outcomes after intratympanic gentamicin in Ménière's disease, but this is a single case report and cannot guide protocol changes without larger studies.

Establishing a systematic multimodal assessment framework for intratympanic gentamicin treatment helps clinicians better understand the trade-off between vestibular ablation (reducing balance function) and hearing preservation in Ménière's disease management.

1. 01Single case report plus focused review of intratympanic gentamicin for vestibular drop attacks in Ménière's disease.
2. 02Multimodal audiovestibular battery used to track hearing and balance function before and after treatment.
3. 03Gentamicin is ototoxic (can damage hearing) and ablates vestibular function; the trade-off is central to management.
4. 04Focused review contextualizes the case within broader evidence on intratympanic gentamicin outcomes.
5. 05Published in Diagnostics (doi: 10.3390/diagnostics16121860).

PMID

42351519

DOI

10.3390/diagnostics16121860.

Journal

Diagnostics

Publication type

case_report

Evidence level

4

Sample size

1

Population

Patient with Ménière's disease experiencing vestibular drop attacks treated with intratympanic gentamicin

Intervention

Intratympanic gentamicin injection with multimodal audiovestibular assessment