Concurrent VVOR and VORS profiling reveals a threshold-dependent VOR suppression deficit in vestibular migraine

OBJECTIVES: To define the dual profile of visual-vestibular integration in vestibular migraine (VM) by concurrently evaluating visually enhanced vestibulo-ocular reflex (VVOR) and vestibulo-ocular reflex suppression (VORS), and to determine which metric more closely reflects disease-related central vestibular dysfunction.

Audiologists and vestibular specialists should be aware that concurrent VVOR/VORS profiling may help identify a threshold-dependent VOR suppression deficit specific to vestibular migraine, potentially improving differential diagnosis — but clinical validation in larger cohorts is needed before changing testing protocols.

Characterising a threshold-dependent VOR suppression deficit in vestibular migraine could refine vestibular function testing and improve differentiation of this condition from other balance disorders seen in audiology clinics.

1. 01Concurrent profiling of VVOR (visual-vestibulo-ocular reflex) and VORS (VOR suppression) used in vestibular migraine patients.
2. 02A threshold-dependent deficit in VOR suppression was identified, appearing only above a stimulus intensity threshold.
3. 03Findings may help distinguish vestibular migraine from other vestibular disorders in clinical testing.
4. 04Published in Frontiers in Neurology (2026); study population and sample size not specified in abstract.
5. 05Results are preliminary and require replication in larger, controlled cohorts.

PMID

42388699

DOI

10.3389/fneur.2026.1872711.

Journal

Frontiers in Neurology

Publication type

research_article

Evidence level

4

Population

Patients with vestibular migraine

Intervention

Concurrent VVOR (visual-vestibulo-ocular reflex) and VORS (VOR suppression) profiling