Vogt-Koyanagi-Harada (VKH) disease is a multisystem autoimmune disorder characterized by an inflammatory response targeting melanocyte-associated antigens in tissues such as the uveal tract, inner ear, meninges, and the skin. The classic presentation is bilateral pan-uveitis (choroiditis and multifocal serous retinal detachment) in association with extra-ocular features such signs of meningeal irritation (headache,...
Audiologists and otologists should consider VKH disease in patients presenting with audiovestibular symptoms alongside eye inflammation or skin/hair changes, as misdiagnosis can delay sight- and hearing-preserving immunotherapy.
Raising awareness that VKH disease can mimic common neurological diagnoses is critical for preventing irreversible hearing and vision loss through timely immunosuppressive treatment.
- 01VKH disease, a rare autoimmune disorder targeting pigment (melanocyte) cells, can present with hearing and balance symptoms.