Objectives : Temporomandibular disorder (TMD) is a multifactorial condition that significantly affects patients' quality of life. This study investigated the association between clinical, biopsychosocial, and genetic factors, including the MMP3 rs679620 polymorphism, and TMD in women from southern Brazil....
✦ The floor
Discussion
Signed responses from readers of the wire.
No immediate practice change for audiologists; however, the findings reinforce the relevance of biopsychosocial screening and possible genetic factors in TMD, which is pertinent for audiologists managing patients with ear symptoms (tinnitus, otalgia) of suspected jaw-joint origin.
Understanding the biopsychosocial and genetic contributors to TMD may help audiologists better triage patients with ear symptoms that overlap with jaw-joint dysfunction.
- 01Study investigated clinical, biopsychosocial, and genetic (MMP3 polymorphism) factors in female TMD patients.
- 02TMD frequently presents with ear symptoms including tinnitus and otalgia, overlapping with audiology practice.
- 03MMP3 (a gene involved in tissue breakdown) polymorphism was assessed as a potential risk factor.
- 04A biopsychosocial model was applied, recognizing that psychological and social factors influence TMD.
- 05Published in Diagnostics (PMID 42510142).
Biopsychosocial factors are associated with TMD severity in women.
studypartially supportedMMP3 gene polymorphism is associated with TMD in women.
studyunclear- PMID
- 42510142
- DOI
- 10.3390/diagnostics16142280.
- Journal
- Diagnostics
- Publication type
- research_article
- Evidence level
- 3
- Population
- Women with temporomandibular disorder (TMD)
- Intervention
- Assessment of clinical, biopsychosocial factors and MMP3 gene polymorphism
Primary outcomes
Association between MMP3 polymorphism and TMD; Association between biopsychosocial factors and TMD clinical presentation