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Caloric-vHIT Dissociation in Vestibular Migraine: An Observational, Retrospective Case Series Study

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: Caloric-vHIT (CalHiT) dissociation has been considered highly characteristic of Ménière's disease (MD), but its occurrence in vestibular migraine (VM) remains incompletely characterized. Objective : The primary aim was to characterize, through detailed longitudinal analysis, the clinical and mechanistic heterogeneity underlying caloric-vHIT dissociation in seven patients with definite VM in a retrospective cohort....

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Discussion

Signed responses from readers of the wire.

Clinical Takeaway

Caloric-vHIT dissociation appears in a subset of vestibular migraine patients; clinicians should factor this pattern into differential diagnosis to avoid misclassifying vestibular migraine as Ménière's disease, though the retrospective case-series design limits the strength of this guidance.

Why It Matters

Distinguishing vestibular migraine from Ménière's disease is a persistent clinical challenge, and characterizing test-dissociation patterns could refine diagnostic protocols and reduce misdiagnosis rates.

Key Points
  1. 01Caloric-vHIT dissociation — mismatched results between two inner-ear function tests — was identified in vestibular migraine patients.
  2. 02The dissociation pattern in vestibular migraine was compared to that seen in Ménière's disease.
  3. 03Retrospective case-series design limits causal inference and generalizability.
  4. 04Findings may help clinicians navigate a common and difficult differential diagnosis.
  5. 05Results support considering test-battery context when interpreting vestibular function.
Claims & Evidence

Caloric-vHIT dissociation occurs in vestibular migraine patients at a characterizable frequency and pattern.

studypartially supported

The dissociation pattern in vestibular migraine differs from that in Ménière's disease.

studypartially supported
Research metadata
PMID
42513282
DOI
10.3390/jcm15145369.
Journal
Journal of Clinical Medicine
Publication type
research_article
Evidence level
4
Population
Patients diagnosed with vestibular migraine
Intervention
Caloric testing and video Head Impulse Test (vHIT)
Comparator
Patients with Ménière's disease

Primary outcomes

Frequency of caloric-vHIT dissociation; Pattern characterization of dissociation in vestibular migraine vs. Ménière's disease

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