VP and MS are distinct clinical entities arising from the peripheral vestibular system and central extrapyramidal pathways, respectively. We report a rare case of a 69-year-old woman with coexistence of VP and MS. Individualized pharmacotherapy resolved vertigo and markedly improved blepharospasm. MRI and multidisciplinary collaboration were key.
✦ The floor
Discussion
Signed responses from readers of the wire.
No actionable change—single case reports of rare co-occurrences are hypothesis-generating only and do not support changes to clinical assessment or treatment protocols.
This rare co-occurrence highlights the potential for simultaneous peripheral vestibular and central movement-disorder pathology, reminding clinicians to consider multisystem diagnoses in complex dizziness presentations.
- 01Single case of a 69-year-old woman with both vestibular paroxysmia and Meige syndrome.
- 02Vestibular paroxysmia involves brief, sudden spinning episodes due to nerve compression.
- 03Meige syndrome causes involuntary muscle movements of the face and jaw (a movement disorder).
- 04Rare co-occurrence of peripheral vestibular and central extrapyramidal pathology.
- 05Published in Clinical Case Reports (2026).
Vestibular paroxysmia and Meige syndrome can co-occur in the same patient, involving both peripheral vestibular and central extrapyramidal pathways.
studypartially supported- PMID
- 42756764
- DOI
- 10.1002/ccr3.73547.
- Journal
- Clinical Case Reports
- Publication type
- case_report
- Evidence level
- 4
- Sample size
- 1
- Population
- 69-year-old woman with vestibular paroxysmia and Meige syndrome
- Intervention
- Clinical evaluation and documentation of co-occurring vestibular paroxysmia and Meige syndrome
Primary outcomes
Description of clinical presentation of co-occurring conditions; Diagnostic and management considerations