MRI Findings Suggestive of Trigeminal and Vestibulocochlear Nerve Involvement in Miller Fisher Syndrome

Miller Fisher syndrome (MFS) is a variant of Guillain-Barré syndrome characterized by a triad of ophthalmoplegia, ataxia, and areflexia, typically associated with anti-GQ1b antibodies. While cranial nerve enhancement is sometimes seen on high-resolution MRI, involvement of the trigeminal (CN V) and vestibulocochlear (CN VIII) nerves is rare....

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No actionable change to audiology practice; however, clinicians evaluating patients with Miller Fisher Syndrome should be aware that hearing (vestibulocochlear) nerve involvement, while rare, may occur and could present with auditory or vestibular symptoms.

Documenting cranial nerve involvement beyond the classic triad in Miller Fisher Syndrome broadens the differential for unexplained vestibular and auditory symptoms in patients with known or suspected autoimmune neuropathy.

1. 01MRI showed involvement of both trigeminal and vestibulocochlear nerves in a Miller Fisher Syndrome patient.
2. 02Miller Fisher Syndrome is a variant of Guillain-Barré syndrome, typically presenting with ophthalmoplegia, ataxia, and areflexia.
3. 03Vestibulocochlear nerve involvement expands the known cranial nerve manifestations of the syndrome.
4. 04This is a single case report; findings require confirmation in larger studies.
5. 05Auditory or vestibular symptoms in Guillain-Barré-spectrum patients may warrant MRI evaluation.

PMID

42924777

DOI

10.3390/reports9040325.

Journal

Reports

Publication type

case_report

Evidence level

4

Sample size

1

Population

Single patient with Miller Fisher Syndrome

Intervention

MRI evaluation of cranial nerve involvement in Miller Fisher Syndrome