Ménière's disease (MD) is an inner ear disorder characterized by unpredictable vertigo attacks, tinnitus, and aural fullness, ultimately leading to a decline in audiovestibular function. Linked to endolymphatic hydrops (EH), MD often progresses to bilateral involvement (BMD). When conservative therapies fail, MD requires destructive treatments....
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Discussion
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Results from this prospective study may inform consideration of pressure therapy as a management option for bilateral Ménière's disease, but without a control arm the evidence remains preliminary — no immediate practice change is warranted pending controlled trial data.
Bilateral Ménière's disease is particularly disabling and has limited evidence-based treatment options, making any prospective outcome data valuable for guiding clinical decisions.
- 01Prospective design evaluated pressure therapy specifically in bilateral Ménière's disease.
- 02Bilateral Ménière's disease involves vertigo, tinnitus, and progressive hearing and balance decline in both ears.
- 03Pressure therapy devices (e.g., Meniett) deliver low-pressure pulses to the middle ear.
- 04No comparator arm is mentioned, limiting causal inference.
- 05Findings may support pressure therapy as a conservative, non-surgical option for a difficult-to-treat population.
Pressure therapy provides measurable benefit for patients with bilateral Ménière's disease.
studypartially supported- PMID
- 42732621
- DOI
- 10.65717/iao.2026.262419.
- Journal
- International Archives of Otorhinolaryngology
- Publication type
- research_article
- Evidence level
- 2b
- Population
- Adult patients with bilateral Ménière's disease
- Intervention
- Pressure therapy (low-pressure pulse delivery to the middle ear)
Primary outcomes
Vertigo control; Audiological outcomes (hearing thresholds); Tinnitus severity