With further research on the relationship between gut microbiota and human health, discussions on various gut-X axis have been increasingly prevalent. Evidence indicates that microbiota dysbiosis is closely linked to the onset and progression of audiovestibular disorders and the gut-ear axis has gradually been recognized as a vital systemic regulatory pathway....
✦ The floor
Discussion
Signed responses from readers of the wire.
No actionable clinical change at this stage; the gut-ear axis is an emerging research concept and current evidence does not support microbiome-targeted interventions for auditory or vestibular disorders in routine practice.
Establishing a mechanistic link between gut microbiota and auditory/vestibular health could open entirely new preventive and therapeutic avenues in audiology.
- 01Review explores the proposed gut-ear axis connecting intestinal bacteria to hearing and balance disorders.
- 02Gut dysbiosis (imbalance of gut bacteria) is hypothesised to contribute to auditory and vestibular pathology.
- 03Mechanisms may involve systemic inflammation, immune modulation, and metabolic signalling.
- 04Evidence is largely preclinical or observational; no clinical interventions are validated yet.
- 05Highlights a growing interdisciplinary research area between gastroenterology and audiology.
Gut microbiota dysbiosis is associated with the development of auditory and vestibular disorders.
studypartially supported- PMID
- 42737427
- DOI
- 10.3390/ijms27177523.
- Journal
- International Journal of Molecular Sciences
- Publication type
- review
- Evidence level
- 5
- Population
- Not applicable — narrative/systematic review of existing literature on gut microbiota and auditory/vestibular disorders
- Intervention
- Gut microbiota dysbiosis (exposure)
Primary outcomes
Association between gut microbiota composition and auditory disorders; Association between gut microbiota composition and vestibular disorders